Advice Pool - Real Estate

There are three types of possible commissions during a real estate

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

transaction:

The seller’s real estate agent commission
The

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

buyer’s real estate agent commission
The mortgage broker or

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

enders commission

All of these can change from deal to deal.

Rea

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

estate agents

The seller’s real estate agent is the “listing bro

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

er”. If another real estate agent brings a buyer to the table, the

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

n typically the commission is split between the buyer’s and seller

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

s agents.

These commissions are usually around 6% or lower, and a

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

e negotiable.

Mortgage broker (or lender)

The mortgage broker, i

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

you use one, essentially charges fees two different ways. One may

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

be “flat fees” such as processing fees or admin fees. The other ty

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

pes of fees are variable such as the “points” you may pay. A “poin

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

” is 1% of the loan size. If the loan size is $400,000 and you are

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

charged two points, you are being charged $8,000 (2% of the $400,0

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

0 loan).

A lender will either charge you upfront the way a mortga

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

e broker does, or offer you a higher interest rate to increase the

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ir profits.

A lender is not necessarily cheaper than a mortgage b

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

oker. If they always were, no one would be in the mortgage brokeri

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

g business.

For more information visit elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

://www.archerpacific.com/">www.archerpacific.com Loan Library

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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