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For many of us hobbies are an interesting and pleasurable way to spend some of our spare time. And often what starts out as something that we have a minor inte

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

rest in, can quickly turn into something that begins to take up a much larger part of our life both in terms of the time and money we spend on it.

One such ho

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

by that can quickly take over a large proportion of the enthusiasts life is coin collecting.

A major difference between many collecting hobbies and coin colle

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

cting is that with coin collecting the collectables can be worth very large amounts of money. It is at this point that the collector is no longer just a "hobbi

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

st", but is as much an investor, with decisions about what coins to buy and sell largely being made by how much money can be made on a sale or saved on a purch

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

se.

Coin collecting historically, was done as a way to preserve and hopefully increase wealth. Coins where accumulated and saved in the hope that their value

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

would appreciate. In times past coins were of such value that only royalty had sufficient wealth that would enable them to "collect" coins.

These day's anyone

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

can collect coins. Many start as young children who are given a few coins by a relative, and from these humble beginnings an interest grows which may some day

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

become a very real money making proposition.

With the arrival of the internet, many collectors are now looking at their collections as having some significant

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

monetary value. Online auctions such as Ebay have many auctions for coins from all over the world running every day, with many of these auctions giving sellers

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

a very good return for their coins.

A significant part of the popularity of coin collecting is it's accessibility. Anyone can start a collection. The change f

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

rom the supermarket could be the first coins in your collection. In the early stages most coin enthusiasts put any coins they come across in their collection.

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ith experience and time spent actually studying coins, most collectors become a bit more discerning.

Many collectors begin to specialise in coins made of a ce

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

rtain metal such as copper coins, bronze coins, silver coins etc. Some prefer coins of a particular age or time or location.

Usually by this point, the collec

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

or is becoming more serious and is considering the value of their coins much more, as well as being happy to spend more on a coin that they feel will enhance t

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

eir collection or simply make a good return on their purchase cost at some point in the future.

If you are thinking of starting a coin collection it may be us

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

eful to determine what you are looking to get out of being a collector. If you are looking for a pleasurable past time without much concern for what your colle

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

tion is worth or may be worth some time in the future, coin collecting will give you a lot of pleasure with minimal expense.

If on the other hand you are look

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ing at coin collecting as an investment and possible income stream, start hitting the books and spending some time investigating auctions and the marketplace t

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

see what is in demand. Start with money you can afford to invest and buy in small quantity. As your experience and knowledge grows so should your bank balance

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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