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Over the past 2 years it seems the state of pro women's wrestling has greatly disintegrated. The WWE suffered a big loss wi

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

th the departure of WWE Diva Trish Stratus. Trish Stratus, without a doubt, was an icon in the world of women's wrestling.

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

rish was arguably the best female wrestler to ever grace the squared circle. Now with Trish Stratus removed from the WWE, t

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

here are only a handful of decent female wrestlers left. Amy Dumas aka Lita is one of them wrestlers. However, it has been

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

eavily rumored that Lita will be retiring from the WWE as well. Lita has also immensely toned down her mexican-luchador wre

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

stling style. Nonetheless, if the rumors are true, the world of professional woman's wrestling would be suffering another h

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ge loss.

I would say from 2001-2004, women's wrestling really made its way back on the map. The WWE roster contained many

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

great female competitors during this period. I mean you had Jazz, Nora Greenwald (Molly Holly), Gail Kim, Victoria, and of

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ourse Lita & Trish Stratus just to name a few. What credible professional female wrestlers are left? In TNA, I believe Gail

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

Kim is the only decent female wrestler in the company. Unfortunately, for the most part, Gail has been limited to being a

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

manager. In the WWE there are WWE Divas Victoria, Mickie James, and perhaps Jillian Hall. Victoria has so much wrestling ab

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

lity, and in my opinion, is the most deserving of holding the WWE Women's Championship. I hear that Beth Pheonix is a reall

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

y hard worker, and potentially a great wrestler. I also hear the same of Melina Perez. Most of the remaining WWE Divas are

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

bunch of former diva search contestants who mainly make up the T & A factor. Now as a webmaster of a WWE Divas site, I ce

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

rtainly am appreciative of the beauty these women possess. I just feel these woman could and should be used in a more effec

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ive way.

It seems that all of the great female wrestlers out there are working in the independent circuit. The WWE and/or

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

TNA could snatch these ladies up whenever they want. The only question that remains is why haven't they done so yet? Well,

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

nfortunately, it seems professional women's wrestling isn't a high priority nowadays. It seems in their eyes, T & A is much

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

more over with the fans than seeing these women wrestle. So I ask you, the wrestling fan, what would you rather see? Is wo

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

en's wrestling dead? Will it ever be resurrected to the state it was a few years back? The answer lies in the hands of time

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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