Advice Pool - Relationships

Does your marriage revolve around your children or grandchildren? Do you and your spouse spend too much time apart? Have you grown apart? Imagine your marriage 20 years from now. How i

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

s it going to be if you keep up with your current approach? If you don't like the thought of your future with its present course, then your marriage may need a spring cleaning.

Ernest Ho

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

lmes said, "Life is a mirror and will reflect back to the thinker what he thinks into it." Have your thoughts undermined a once great relationship? If so, you can redirect your thoughts

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

and thus redirect the future of your marriage. Most couples put more effort into the planning of their vacation than they do their marriage.

Remember the days of dating each other? You

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

couldn't get enough of each other and gladly gave a lot of attention to your partner. After a couple gets married they are pulled apart by things like their career and the needs of their

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

children. A routine develops and if the couple isn't careful, so does a sense of boredom.

Unfortunately, your spouse tends to get blamed for the boredom. But don't be too quick to judge

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

. Simply because you have been together for a number of years doesn't mean that you know your spouse today. People change. As men get older, they tend to shift focus from their career t

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

o their family. Women tend to go in the direction of career because they have put their career pursuits on hold for the sake of their children.

The goals you had early in the marriage ha

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ve probably changed. But your partner may have the assumption that you still want things the way they were in the beginning. Especially in the ages between 35 and 55, what's important to

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

you and what matters most are usually being re-evaluated. Talk with your partner about what is really important to you. What would make your life more satisfying? Listen to your spouse

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

. Encourage them to share their views. Be open to what they say. Don't be too sensitive or defensive. Don't be judgmental. It doesn't take a rocket scientist to figure out that if you

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

overreact to what they say, your spouse isn't going to talk to you.

Try to be accepting and positive of what your spouse has to say even if what you hear surprises you. If you have a ha

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

rd time keeping your mouth shut, I suggest you sit on your hands. Somehow this simple behavior helps you keep quiet so that you just listen. Remember, one good idea could be life changin

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

g to your marriage.

Be curious and eager to know your spouse all over again. It doesn't take both of you to do the spring cleaning, even though it helps. You'd be surprised by what one

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

dedicated spouse can do. And just like the spring cleaning of your home, your marriage deserves many cleanings. Keep your marriage fresh and alive. Tap into your ability to dream again.

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

Rediscover the beauty of your husband or wife. Take one step today towards the renewing of your marriage. Then take another step tomorrow. And so on and so on..

Here are some additio

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

nal "cleaning solutions" for your marriage.

1. Try to see your spouse with fresh eyes.
2. Keep your mind focused on your spouse's positive qualities.
3. Forgiveness is letting g

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

o of the past. Forgiving yourself and your spouse is an attribute of the strong.
4. If you are keeping score of your spouse's mistakes, you are setting your marriage up to fail.

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

>5. Life is too short to allow boredom to infiltrate your marriage.
6. Good things often come from the difficult times.
7. Strive to genuinely understand your spouse.
8. B

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

reak your routines to keep the marriage exciting.
9. Maintain an attitude that encourages openness.
10. Strive to find the magic that is waiting to be discovered in your spouse.

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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