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  • Advice Pool - Made In Heaven, Finished In Hell - Part 2

    ...continued from Part 1

    Curiosity doesn't always kill the cat

    As Isaac Asimov wrote in his New Guide to Science, 'almost in the beginning was curiosity'. Now, relationships are
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    as far removed from science as a Van der Graaf generator is from a blender, but the same rule applies.

    Being inquisitive is a relationship's carrot on a stick. Showing zeal and
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    believing that the other can still intrigue you with new things is essential for a relationship's growth. You need to yearn for your partner, ask questions, call or message when a
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    part and show interest when together.

    Curiosity should not be mistaken for nosiness, and if your partner calls you every two seconds to ask for the exact latitude and longitude o
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    your position, then probably you are going out with a stalker. So do not poke your nose into delicate affairs such as who has he phoned lately, otherwise, curiosity may kill the
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    cat.

    Do things together

    The most successful couples are those who, even if they have a busy schedule and their diary is choc-a-block with appointments, make spending time togeth
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    er a priority.

    Share your hopes, fears and dreams with your partner and keep in touch with what is happening in your lives. Make sure that every second with your partner counts b
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    ecause being together is about quality time rather than rotting in front of the telly without saying a word. Of course, making time entails sacrificing other activities, but quali
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    y time is an investment in your future happiness.

    Spending time with each other, exploring new things and doing favours for your partner are important. A successful relationship
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    is a tennis-like exchange of favours; a back and forth of reciprocity because it is just nice to do things for your partner.

    Does it need fixing?

    YOU KNOW YOUR RELATIONSHIP WORK
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    S IF:

    • Both of you accept change as an inevitable part of life and adapt to it together

    • You do not look at other people's relationships for solutions

    • You are both committe
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    d to each other

    • There is a mild and healthy level of jealousy which protects your relationship

    • You look after your partner and give each other confidence.

    YOU SHOULD LEAVE
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
    OUR PARTNER IF:

    • You are no longer able to communicate your feelings

    • You are willing to let your relationship suffer in order to dedicate more time to work, business or frien
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    ds

    • Your relationship has become a conflict cycle and arguing leaves you hurt and wondering if you want to stay

    • You are being emotionally or psychologically bullied

    • There
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    is violence or threats of violence and your partner is aggressive - remember that there is life after an abusive relationship.

    Be your own PR agent

    Good communication is the onl
    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    y way you can openly and honestly tell your partner who you are, what you want and how you feel. When we talk and listen, we are giving each other the entry pass for our private t
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    oughts and emotions. Make sure you sit down and have a nice talk not only when trouble looms ahead but also as part of your relationship maintenance routine.

    It is also important
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    to accept that we all have our differences and that arguments are a normal part of every relationship. However, stick to productive rather than destructive arguing - a good argum
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    ent is an opportunity to share feelings, strengthen your bond and compromise while admitting that your partner may have different opinions than yours.

    Effective communication is
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    also when we are polite and show respect to each other. Being in a relationship with someone does not mean that you or they should throw 'please' and 'thank you' out of the window


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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