Advice Pool - Relationships

Just when a relationship is going well – the laughter, the romance, the comfort of belching in front of your partner – a great shadow looms over it. This shadow - carrying a one way ticket and a month’s worth

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

of luggage – can only be one thing: your future in-laws.

Whether they come to visit you or you go to visit them, meeting your future in-laws for the first time can be unsettling. You want to be char

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ming and appeasing. You want to be witty and intellectual. You want to be intelligent and intuitive. You want to be free of any giant pieces of food stuck in your teeth.

While meeting your future i

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

n-laws seems like a difficult task – as if every pair of in-laws resembles the parents on Everybody Loves Raymond – there are things that can be done to make a first time meeting a little less awkward

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

and a little more comfortable.

Know Your Stuff
Before meeting your partner’s parents, have him or her provide you with a little “Mom and Dad: 101.” Learn what your future in-laws like, w

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

hat they don’t like, and what they are adamantly against. If your partner’s parents are extremely religious, or unyieldingly democratic, you should probably be given a heads up. This is merely to prevent you f

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

rom saying things that you don’t find offensive, but that they might. If your future in-laws are unyieldingly democratic, for instance, you might not want to reveal your “Reagan Forever” tattoo just yet.

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

Be Polite
There is a fine line between being fake and being polite. While you want to be cordial, you don’t want to teeter on the brink of obvious flattery and empty compliments. Convey your

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

politeness by using correct grammar, saying “please” and “thank you,” and offering to help set the table or mix the cake batter. However, don’t be overly polite to the point that it looks like you’re acting: o

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

ffering to help with the dishes is one thing, offering to paint a China pattern in your future mother-in-law’s likeness is a whole different ballgame.

Don’t Pick Fights with Your Partner

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

When meeting your future in-laws, keep in mind that they are the parents of your partner, protective of him or her like a mother bear protects her cubs. Because of this, picking a fight with or even criticizi

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

ng your partner in their presence will not end favorably for you. As you make a negative remark at your partner’s expense, you will find your future in-laws banding together, snapping in unison like a scene fr

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

om West Side Story. Until you get to really know your future in-laws, don’t try to get them on your side. You see, we build to that.

Show Interest
Your future in-laws, assuming t

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

hings go well, will likely become your present in-laws. Because of this, you better become interested in them: they will become your family. So, ask about Uncle Bob or Cousin Billy. Listen intently as they tal

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

k about their grandparents or Aunt Lila’s sixth wedding ceremony. Ask questions and make comments that let them know you care. Showing interest in someone, or someone’s family, is one of the best ways to make

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

them interested in you.

Meeting the future in-laws can often rank near getting a tooth pulled or a mole removed on the spectrum of fun. Yet, it’s part of a relationship: unless you meet a partner wh

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

o was raised by wolves, chances are he or she has a family. Meeting the in-laws for the first time is probably the most intimidating: it does get easier. Eventually you may find comfort in the relationship you

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

have with your in-laws – loving them, relying on them, and asking them for money.

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.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

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tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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