Advice Pool - Relationships

• Be yourself—avoid comparing yourself to others. Accept yourself as you are now, but be willing to change. Be hone

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

st, honor your integrity and be emotionally open.

• Look people directly in the eyes—avoid staring or glaring. Whe

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

n you communicate, concentrate on direct eye contact. This is an important non-verbal indicator of self-confidence

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

and shows interest in the other person.

• Find positive attributes in people. It is easy to find fault and negati

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ves. Illuminating another’s positive attributes enhances their self-esteem and yours. You cannot recognize a posi

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

tive attribute in another without having the same attribute. Thus, when you illuminate another’s positive attribut

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

you are illuminating your own as well.

• Write all the positive attributes about yourself and others—you can use

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

this as a reminder when things seem difficult in the relationship.

• Smile! Your smile is your best feature. You

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

r smile is the window to your inner being—let your light shine for others to see.

• Be affectionate daily with you

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

significant other. Research shows that people who regularly give and receive affection live longer and are less st

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ressed. Make a habit of greeting a loved one with a hug and a kiss.

• Set boundaries—no matter how difficult—to t

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

ake care of yourself.

• Be clear about who you are and what you want—your limits regarding time, money, and things

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

you will or won’t engage in.

• Share your dreams, wishes and hopes—knowing that you might not complete them. Encou

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

rage your significant other/friends to share theirs.

• Explore the options for taking care of recreational needs.

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

Make a list of likes and dislikes and share this list with your significant other/friends. Ask them to share their

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

eeds as well.

• List your priorities and do more things that give you energy.

• Have fun—skip, sing, dance, be si

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

lly—let yourself be carefree.

• Take a mental health day (R&R) without guilt or regret. Read a book, garden, take

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

a walk, climb a hill, be near water, nature and fire, or sit and do nothing.

• Give undivided time and attention e

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ch week to those close to you.

• Say, ‘NO’ without guilt or regret to requests outside your energy/boundary level.

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

• Make time for friends. Friendships need nurturing.

• Remember time spent with someone is a way of showing love

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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