Advice Pool - Relationships

It's time: you're going to pop the question. A wedding proposal should be one of the most memorable events in both of your lives, and getting it right is a great start to your lives as a marri

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ed couple. Think about your partner as you plan your wedding proposal - don't worry about what you've seen on TV, or what others have done before you... it's a personal experience and you can

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ustom-tailor specifically for the two of you.

What Not to Do

Before we get to the good stuff, here are a few "misadventures" to avoid when proposing marriage:

Do not tri

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ialize the proposal. You're asking someone if they want to spend the rest of your lives together, not what they want to eat for dinner.

A marriage proposal is meant to be a spe

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ial and memorable occasion for you as a couple, so don't allow relatives or friends to invite themselves along when you know you're going to pop the question.

Don't propo

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

e at someone else's special occasion, like a wedding, baby shower, etc.. First of all, it's not polite to detract from someone else's special day. And secondly, it's best to make a special

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

day for just the two of you.

Don't put your partner on the spot, such as proposing in public in a situation where they feel forced to say yes (then privately say no).

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

Timing & Location

Many people have remarked that their marriage proposal was less romantic than they had hoped. Of course, the proposal makes up just a small part of your relat

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

onship, but it's still nice to be look back upon it with fond memories.

Talk to friends and family members of your future spouse to get additional ideas what your partner considers romantic.

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

ou will have some ideas as well, but it's nice to have more feedback from people who also know your partner well.

Ask for help in the romance department by calling establishments in the area

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

nd asking for their assistance. Often times they'll be willing to assist you in creating the right mood for that special moment.

For instance, if you're think about proposing in the Rocky Mou

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

ntains, call a local tram operator and ask for their suggestion. They may be willing to help you arrange for a special floral arrangement to greet your partner when you reach the top... or cre

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

te other ways of setting the mood. We even heard of a gent who asked the tram operator if he'd be willing to stage a false-malfunction and stop the tram at midpoint in order for the couple to

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ave the perfect opportunity!

But remember, romance has no rules and can't be planned or predicted. If the emotions are right and the setting is perfect, popping the question right then and th

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

re may make for an excellent opportunity. For example, one couple was enjoying a coastal hike on Vancouver Island when they inadvertently got soaked from an incoming rain storm. The rain was d

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ipping from the forest canopy, the wildness sounds were soft and the emotional timeliness was perfect. Even though a ring wasn't available at that moment, the question was popped and the coupl

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

announced their engagement.

Costs

You can spend hundreds or even thousands of dollars on setting the most romantic of moods, but the setting depends on what you and your spouse consi

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

er romantic. Romance isn't about the amount of money you spend, its about connecting emotionally with another person and making each other feel special.

Your partner's idea of "romance" may m

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

an secluding yourselves in a private little cottage by the sea, just the two of you alone with nature. Or maybe your partner loves big sweeping gestures, like a romantic helicopter tour to the

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

top of a mountain. Whatever the case may be, tailor it to your partner's tastes.

Budget appropriately for your wedding proposal... but remember that you'll also need to budget for the wedding

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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