Advice Pool - Relationships

There is this woman at my son’s school with whom I have a very bad human connection indeed. I think she is unapproachable, indifferent, and unfriendly. In fact, though I lik

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

e a few people, there are more people in that school whom I absolutely dislike. In my book they are all indifferent, unapproachable, and unfriendly.

On the other hand I hav

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

e a great human connection with my piano teacher, now a friend, who is just delightful, warm, interesting, generous, and very intelligent. Ditto for my son who is also very

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

intelligent, sensitive, caring, loving, and absolutely hilarious.

How is that that I have great and not so great relationships with different people? What is there that mak

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

es me like and be liked as well as hated (or disliked) and hateful (or despising)? Why do I recognize negative qualities in some people and positive qualities in other peopl

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

e?

The answer is very simple: I am just mirroring myself in these people. As we hate to realize it, the truth is that we all have positive and negative qualities (according

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

to our values, of course) that we project onto others, thus, some people push our buttons whereas others just delight us.

It is, thus, crucially important to know who are

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

we exactly, so we can transform all our relationships into positive and gratifying ones. To know our qualities we need only make two lists. For each list, get a piece of pap

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

er and make a line in the middle.

In the first sheet, do the following:

1. Write on top: Qualities I appreciate in others.

2. On the left hand side of the paper, write th

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

e names of people you most admire. They can be real people or imaginary characters, dead or alive, that you have or have not known personally; it matters not.

3. On the rig

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ht hand side of the paper, for each person, write all the qualities you most admire in them.

4. Keep doing this until you have written qualities for all of the people in th

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

at list.

5. Do not repeat qualities. Write them only once.

In the second piece of paper do the same, only this time, you will write: “Qualities I despise in others,” meani

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ng all the negative qualities certain people have that you truly despise, even hate. Now, pay attention that you should not write about behavior but qualities only.

For exa

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

mple: Hitler = mass murderer. Mass murderer is a behavior, not a quality. You could write instead: Hitler = unsympathetic (to put it mildly). See the difference?

When you

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

are done with both lists write the following at the bottom of each page:
I see these qualities in others because I too, have them.
Ouch! How can I compare m

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

yself with that despicable man?

Now is the time to reflect about each of our negative qualities, the ones we are sure NOT to have but which, indeed we do, in a subtle or no

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

t so subtle way. In our example: unsympathetic. Ok; the guy condoned the murderer of millions of people. In what way are we being and doing the same? You don’t need to go fa

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

r. If you are not a vegetarian, you already have an answer. (This is a lame comparison, I know. I just want to give an example.)

See? It is not difficult at all to see wher

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

e our projections go. Try it and I guarantee your relationships are about to change radically for the better.

By the way: For some reason, I can’t care less about the peopl

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

e in that school. I, too, am indifferent, unapproachable, and unfriendly. It is up to me to change the situation. Once I change, everything will fall into place beautifully.

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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