Advice Pool - Relationships

I see so many couples that have drifted from being close to bein

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

g so far apart. It's amazing but true - couples can drift from s

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

oul mates to room mates before they even realize what is happeni

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ng.

How close do you want to be?

The key question here

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

for partners to consider is just how close they want to be.

In

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

this point we are talking about intimacy (which includes, but is

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

not limited to, sex.)

Emotional intimacy involves so much more

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

than only sex. To be emotionally intimate, you have lo be willi

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

g and able to step into a person's world and see it, feel it and

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

experience it as he or she does. You don't have lo completely u

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

nderstand it or agree with it, you just need to be able to make

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

that emotional leap and connection into the world of your partne

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

.

Two key questions

Two key questions to consider at th

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

is point are:

What have you done lately to draw you and your pa

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

rtner together?

What can you do together on a regular basis, to

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

draw the two of you closer together?

Author Richard Bach wrot

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

about this sense of intimacy in The Bridge Across Forever when

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

he wrote: "There is a kind of love where you are better off toge

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ther than alone."

That is a both a great definition of intimacy

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

and a great goal to constantly work toward in your relationship

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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