Advice Pool - Relationships

Couples who have a very good relationship are not just lucky. Successful, loving relationships do not just happen

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

. The couples who have loving relationships are taking specific actions that people in unsuccessful relationships

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

are not taking.

Good relationships take work, effort and patience. Good relationships don’t just happen; they h

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

appen because there is a commitment and a plan. Over the next several days the following five specific actions wi

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

l be highlighted and are intended to help you and your partner make a plan for your relationship:

Action 1: Kind

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ness to self and other
Action 2: Take personal responsibly for your feelings and needs
Action 3: Orga

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

nizational responsibility
Action 4: Financial responsibility
Action 5; Health and well-being

Action

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

1: Kindness to self and other

People in successful relationships treat themselves and their partner with kindnes

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

– kind words, kind actions, kind looks, kind listening, and kind thoughts. It is far more important to them to b

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

e kind than to try to control their partner with anger, judgment, criticism, irritation, blame, resistance or wit

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

hdrawal. An important piece of my reconciliation with my wife, Mary Beth, was to replace criticism with kindness

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

and support. This single action is perhaps the primary reason we were able to avoid divorce.

One way to show kin

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ness to your partner is to express appreciation at least once a day. At the end of the day, tell your partner thr

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ee things you appreciate - either something your partner is doing now or something more permanent. One example is

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

, “I really appreciate your support and belief in me today.” But so is “You have always had a beautiful smile.”

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

Begin to shift away from any “victim thinking” and replace it with an “attitude of gratitude.” If your partner is

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

annoying you, you have three choices: (1) change it; (2) leave it; or (3) embrace it. If you choose to neither ch

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ange nor leave, then you are responsible for your choice. Therefore, own your choice and begin to appreciate the

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

positive qualities in the situation and do not harbor resentment. Exchange resentment for kindness and watch your

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

relationship become healthier and more intimate.

Next: Take personal responsibility for your feelings and needs

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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