Advice Pool - Relationships

Yes, you’ve read correctly. I don’t like it.

The word “partner” is used very widely by people writing about relationships, including many of our own site contributors. And it’s perfectly underst

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

andable. After all, what better term do we have at our disposal to describe your opposite number in an intimate relationship? While dictionary definitions may differ, its simple meaning is one wh

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

shares or participates with you in a certain enterprise or activity. So it seems quite appropriate.

Yet, the word makes me uncomfortable. I’ll tell you why.

I touched on one reason in one of m

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

early articles on the Web. (See on this site: Give-and-take: Recipe for Success in Marriage?) I don’t think an ideal marriage relationship is a “partnership” in the same sense that we

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

talk about business partnership, for example. When we think of a partnership, we usually think about a contract between two parties. A 50-50 sharing of responsibilities, or the like.

Yet marriag

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

, as I explained, is no business arrangement - or it shouldn’t be. As I explained, if your mind is going to work along the lines of:

“You have needs and I have needs. Maybe, if I satisfy yours,

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ou will satisfy mine. You wash the dishes and I’ll pay the rent. Sundays to Tuesdays I’ll take out the garbage, and for the remainder of the week you will. Other duties will be divided by mutual

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

consent. For every suit I buy, you can buy two pairs of shoes…”

…you’re not very likely to end up with a happy marriage.

OK, now I can hear you say: “Hey Azriel, who’s talking about marriage? Y

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

u can have an intimate relationship between a man and a woman without them necessarily being actually married. That’s why these relationship writers talk about your partner instead of your husban

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

, wife or spouse. It’s a term that includes everybody.”

Aha, a good point! But, you know, that’s exactly my point.

You see, I don’t really believe there can be an authentic, long-lasting, reall

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

happy, relationship of this type outside formal marriage. That, in a nutshell, is the second - and more important - reason why I shy away from the use of the term “partner” in the context of rel

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

tionships.

We know that the number of couples “living together” has risen very dramatically over the past few decades. Often, the rationale is that by “trying each other out” before tying the kn

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

t, they can see how “compatible” they are. Strangely, some of these people seem to be motivated, at least in part, to take this “precaution” by the rising divorce rate.

This is quite ironic,for

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

tudies have shown conclusively that “living together” does not increase the chances of marital success. Quite the contrary, the likelihood of a durable and lasting union is diminished by this arr

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

angement. If living together were a test of marital compatibility, the statistics should show that couples who have lived together first should have stronger marriages.

But the opposite is the c

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

se. Even though the myth persists!

What’s the problem? What’s lacking in the temporary arrangement, when a couple “shack up” together knowing that if things don’t work out as planned… well, no b

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

g deal. It may be a little painful for a day or two, but it’s just a question of packing one’s bags, walking out the door, shaking off the dust and getting on with one’s life.

In marriage, it’s

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ot quite so simple. And that’s a jolly good thing.

If there’s one key word here, that word is commitment. Making a commitment right from Day One.

You see, a newly married couple will make a del

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

berate effort to accommodate each other and please each other, because they expect to be together for life. In other words, their goal is not to test compatibility, but to

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

>build it!

The word spouse, somehow, is not a particularly attractive one. But, where necessary, I would prefer it to partner anytime

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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If you are in sales it makes sense to stay in touch with all your sales contacts and keep doors open. If you blow smoke, lack integrity, pitch too hard then you are liable to piss off your prospect and potential customer and end up losing in the future any sale you might have had.

How would you know what your employees are doing during working hours? An angry employee could cause major damage to your company letting internal top secret information from your company records.

Health care cost is extraordinarily high and is continually getting higher every year. It almost impossible to pay for a serious medical procedure out-of-pocket without help. That is the main function of health care insurance. For a fee they will pay for part or all of your medical bills.

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