Advice Pool - Relationships

The celebration of a wedding is normally a family event. Thus, it is not surprising to find that

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

most of the attendees in any wedding consist of relatives from both sides of the bride and the

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

groom. It is even more traditional that people who are part of the wedding entourage are either

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

he brother, sister, cousin, niece or nephew of the couple to be wed.

For the ladies, the most c

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

oveted position is to be chosen as the maid of honor since the person picked is one whom the bri

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

e considers to be her closest or best friend. Then there are also the bridesmaids and flower gir

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ls to complete the ensemble. On the men’s side, the equivalent position of the maid of honor is

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

the best man. The other members of the wedding entourage are the page boys and the ring bearer.

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

Generally, it is the groom who will decide who he wants to be his best man. It is very rare that

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

the best man is chosen by another person. The groom’s final choice for best man will usually be

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

one of his male best friends. Given that a wedding is a reunion of family and friends, it is nat

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

ural that the groom would want his best friend to share in his joy at the occasion. Aside from h

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

is closest male friend, the groom may also pick his brother to fill the role of the best man. So

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

etimes, the groom may choose a person who is neither his best friend nor his brother, but someon

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

e who is responsible for introducing him to his bride-to-be. In rare cases, the groom may even d

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

cide to have a female “best person”.

Traditionally, the best man should be single since he will

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

also be actively participating in the wedding preparation, hence this can be time-consuming. Th

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

is is not to say that single people have time on their hands! However, it is now acceptable that

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

a married person become the best man. In this case, the groom as well as bride can benefit from

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

the wisdom that will be imparted by a married best man as regards starting and building a family

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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