Advice Pool - Relationships

After a divorce both the man and the woman are usually angry, hurt, and disappointed. They feel that

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

the other person wasted their time and is not good for anything anymore. They just want to be out of

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ach others lives. It doesn’t have to be that way. If you can get past what caused the marriage to fai

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

you may see that the other person is a trusted confidant and good for absolutely everything.

My ex-

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

usband is a wonderful man. We made every attempt to work together as a couple but finally we both rea

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ized that we were too far apart on important issues for us to stay together. We had an amicable divor

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

e and went our separate ways. We had no children together but I remained close to his adult son and g

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

anddaughter. We would see each other on occasion and we both made sure that bank accounts, income tax

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

s, and other matters were taken care of in a timely manner. I felt bad that I had been unable to make

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

this relationship work but glad that we were still civil to each other.

About three years later I wa

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

injured at work. I was incapacitated for several months and needed help with shopping, errands, and

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

my dogs. It was my ex who offered to help me during this time and I truly appreciated it. By then we

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ere not angry any longer and had both moved on emotionally. We were able to enjoy each other as frien

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

s. I trusted him with my finances and knew that he would take good care of the dogs. He was purchasin

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

a truck for his business and I was able to offer him some helpful advice. We had moved past the divo

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ce and into a new phase for our relationship.

Many people I know think that it is strange to remain

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

riends with someone you were once married to. Others think it shows great maturity. We are not concer

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ed with what anyone else thinks. We just know that it is good to have a trusted, special friend in yo

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

r life. Part of it feels good because we both see that we are good people, just not good together as

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

usband and wife. If you have the opportunity to stay friends with your ex I would highly recommend it

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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