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Advice Pool - Haunted: Burying The Ghosts Of Lost Love
Late at night, as you read quietly, before you fall off to sleep...
During a busy afternoon as you run through a crowd, hurrying back to your office or home....
Sitting in a movie theater, a restaurant or waiting for the light to turn...
A sudden thought or image rises within you. It can come as a small nagging feeling
During a busy afternoon as you run through a crowd, hurrying back to your office or home....
Sitting in a movie theater, a restaurant or waiting for the light to turn...
A sudden thought or image rises within you. It can come as a small nagging feeling
According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
or as a wave of emotion that threatens to overwhelm and drown you in the grief of a memory. Either way it's clear; here comes his/her ghost again.
For those who are haunted by a past relationship, the instinctive response is often to run away from these feelings or to pretend they just aren't there. It is also not uncommo
For those who are haunted by a past relationship, the instinctive response is often to run away from these feelings or to pretend they just aren't there. It is also not uncommo
; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.
Examples of combination products may in
Examples of combination products may in
to react by setting your system on "anger mode" and seeing everything and everyone in a negative light. Shutting down all ability to handle even the simple routine tasks of daily life is another response, and one that signals depression. This one needs to be addressed quickly, as it can leave a trail of destruction in it'
lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.
s path.
These defense mechanisms are employed as a way of coping and to "get through the day." However, when these responses become prolonged and ingrained, we can get stuck in the grieving process that accompanies loss. This is where the ghosts come in.
All loss, especially the absence of someone with whom we were intim
These defense mechanisms are employed as a way of coping and to "get through the day." However, when these responses become prolonged and ingrained, we can get stuck in the grieving process that accompanies loss. This is where the ghosts come in.
All loss, especially the absence of someone with whom we were intim
here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
te, results in sadness, anger, denial, fear, depression and guilt. These feelings are normal. However, how we respond to them will make the difference in how well we recover and move on to a new and healthy life.
In order to work through the grief and finally lay those ghosts to rest, you may need some help with the impor
In order to work through the grief and finally lay those ghosts to rest, you may need some help with the impor
d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.
Combination pro
Combination pro
ant do's and do not's of grieving. The following is a basic primer to get you started.
Things To Do:
Acknowledge Feelings
Denial can provide a very short-term way to cope with loss, but will compound the bottling up of destructive feelings that need to find a healthy outlet for expression.
Allowing yourself to fee
Things To Do:
Acknowledge Feelings
Denial can provide a very short-term way to cope with loss, but will compound the bottling up of destructive feelings that need to find a healthy outlet for expression.
Allowing yourself to fee
ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
l, helps you to understand that what you are feeling is normal and therefore, you are not "crazy" or alone. It also opens the way to learning how to cope and move towards a positive resolution. Over time you will learn that feelings won't kill you, and that you are strong and able to confront them and move on.
Express Ang
Express Ang
easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
r Safely and Productively
Fear of our own anger is normal. This is why we have so much difficulty expressing it to others. We imbue it with a power that is beyond our control and something that can only be destructive.
Therefore, we stuff everything inside. Pressure builds and we explode, and out comes the "anger mo
Fear of our own anger is normal. This is why we have so much difficulty expressing it to others. We imbue it with a power that is beyond our control and something that can only be destructive.
Therefore, we stuff everything inside. Pressure builds and we explode, and out comes the "anger mo
nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
nster"; a creation of our own inability to deal with anger when it is at a lower, more manageable level.
There are safe ways to express these feelings. Crying, talking to friends, writing down the feelings and even engaging in some physically demanding labor are all healthy ways to release your anger.
Take Care Of Yourse
There are safe ways to express these feelings. Crying, talking to friends, writing down the feelings and even engaging in some physically demanding labor are all healthy ways to release your anger.
Take Care Of Yourse
and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
f
This seems to be one of the things we most neglect when loss strikes. Not caring for even basic needs is one of the faces of grief. It can also be a sign of a dangerous depression. Therefore, it has to be a priority.
Basic needs are what usually require attention. These include: adequate sleep, eating right, takin
This seems to be one of the things we most neglect when loss strikes. Not caring for even basic needs is one of the faces of grief. It can also be a sign of a dangerous depression. Therefore, it has to be a priority.
Basic needs are what usually require attention. These include: adequate sleep, eating right, takin
ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
care of minimal household and financial responsibilities and attention to personal grooming.
In addition, exercise not only provides a great outlet for stress, it has been proven in clinical trials to be effective in lessening depression in a significant number of people. Regular exercise can also offer assistance to tho
In addition, exercise not only provides a great outlet for stress, it has been proven in clinical trials to be effective in lessening depression in a significant number of people. Regular exercise can also offer assistance to tho
ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.
Following aspects would a
Following aspects would a
se who have difficulty sleeping and heightens self-esteem.
Build and Strengthen Social Supports
A strong social support system is always important. During a time of extremes loss, it is vital to recovery.
Do you have good, supportive friends? Do they have time and energy that they can offer to you during this perio
Build and Strengthen Social Supports
A strong social support system is always important. During a time of extremes loss, it is vital to recovery.
Do you have good, supportive friends? Do they have time and energy that they can offer to you during this perio
dd to the challenges in developing combination products:
Which markets to tap where the combination products can do fairly well?
Which combination prod
Which markets to tap where the combination products can do fairly well?
Which combination prod
of grieving?
What about religious ties? A church, temple or other community of like-minded believers?
Do you have good support from any family members?
What about organizations that you have participated in and given your time and energy to? Can they now give something back to you?
These are a few of the supports that
What about religious ties? A church, temple or other community of like-minded believers?
Do you have good support from any family members?
What about organizations that you have participated in and given your time and energy to? Can they now give something back to you?
These are a few of the supports that
cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
you can turn to. Make sure you PLAN well for weekends, holidays and other significant days. Let people know you want to get together and that you want to get out regularly and stay active and involved. This allows others to offer their support and remember to include you in group activities, etc.
Give Yourself Time
Give Yourself Time
tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
Getting over the loss of someone you love takes time. It is a process. It doesn't take "forever." You will move on and recover. But beware of that feeling that is often expressed of "I don't know what's wrong with me, it's been months and I'm still not over it."
The months SEEM like forever, but you know they are a relati
The months SEEM like forever, but you know they are a relati
t?
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
ely short period of time. You need to give yourself that time or run the strong risk of getting stuck for (perhaps years) in the quicksand of grief.
Set Realistic Goals
This is a time to prioritize and decide what you most want and need and to make a realistic plan for achieving it.
Goals will keep you focused and
Set Realistic Goals
This is a time to prioritize and decide what you most want and need and to make a realistic plan for achieving it.
Goals will keep you focused and
ping new procedures for reviewing their safety, efficacy and quality.
Professional from academic institutions, pharmaceutical industries, health care indust
Professional from academic institutions, pharmaceutical industries, health care indust
on-track. They will provide a compass as you navigate your way to a new life. They will help you to achieve success and to boost your self-esteem. This achievement will help you to feel strong and capable of beginning a new life.
Things To Avoid
When enveloped in grief and loss, we have to be careful not to respond
Things To Avoid
When enveloped in grief and loss, we have to be careful not to respond
y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
n dysfunctional ways. Some classic examples of poor coping behaviors include:
overuse of alcohol
use of illegal drugs
ignoring signs of serious depression
sexual acting out
recklessness with finances
ignoring basic safety and placing self in risky situations
These are all the result of
overuse of alcohol
use of illegal drugs
ignoring signs of serious depression
sexual acting out
recklessness with finances
ignoring basic safety and placing self in risky situations
These are all the result of
.
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
low self-esteem, guilt and feelings of hopelessness. With good supports and the utilization of healthy ways to express feelings, you will be at far less risk of using these self-injurious behaviors.
Remember, we must be willing to accept grief as a possible price of experiencing love. Many, many people have gone through t
Remember, we must be willing to accept grief as a possible price of experiencing love. Many, many people have gone through t
elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.
Companies that provide selfless information through particip
Companies that provide selfless information through particip
e process of loss and despair and come out strong, whole and ready for a new life. Along the way, they often come to know themselves better and to understand what they most need and want from their relationships. Armed with this new experience and knowledge they are then ready to form new, healthy and lasting relationships
tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products
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