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Psychological tests emerged in the 19th century as a way to measure individual differences and further develop a system of personality classification. In the early 190

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

0’s, psychologists developed tests that intended to measure traits and attitudes. Hugo Munsterberg was one of the first scientists to develop a test that measured psyc

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

hological traits required for employees. These selection tests were then used by American Tobacco Company in order to select its conductors. Further spread of psycholo

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ical testing emerged during the World War I. As abilities of soldiers had to be measured, Office of Strategic Services initiated use of testing as part of the selectio

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

n process of soldiers for special missions.

Projective testing was used in 1920s. As part of this testing, respondents are asked to respond to a vague stimulus; as su

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ch, personal fantasies and emotional associations are projected on the stimulus. The stimulus normally was an inkblot that subjects were to describe. Performance situa

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ional testing was developed in 1930’s and 1940’s. Under this testing, examinees are placed to life like or stimulated situations designed to provoke evidence of specif

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ic features of character, attitudes, and characteristics. At the present moment this type of testing is used to assess an employee’s leadership ability. However, initi

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ally these tests were administered to school children in order to identify and measure such behaviour as cheating, stealing, and lying. Further, services developed a p

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

rformance test as a way to assess emotional and social behaviour. Based on this type of testing, modern rating scales and standardized questionnaires were developed th

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

at are used in employee screening.

In contemporary work environment, there are several hundreds of personality tests. However, all personality tests can be subdivided

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

into two major groups: objective and projective. Objective tests are normally administered on a group basis and are generally referred to as self-reporting inventorie

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

with true or false type of questions. Interest inventories are a common type of objective tests that measures individual’s interest and attitudes towards a certain ty

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

pe of activities.

Objective tests can further be subdivided into two broad subcategories: normative and ipsative. Normative questions correspond to specific qualitie

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

s or scales being measured and, consequently, each question is scored for a specific scale. Ipsative tests, on the other hand, require examinee to choose between two r

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

sponses that measure for different qualities or scales. As such, choosing between either one or the other option indicates examinee’s preferences, attitudes, and abili

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ties in either one quality or the other.

Pre-employment screening has come under a lot of criticism for invading individual privacy, inability to consider multiple si

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

tuational factors that influence human behaviour, overlooking personal motivation, which is a rather strong stimulus when it comes to employee work performance, overlo

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

king the impact of personality testing on the handicapped, ignoring of stress factor and its’ impact on examinee’s responses. Even though personality testing are not t

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

he best predictor of employee work performance, they still are being used more and more widely in employer’s attempt to hire the most productive and reliable employees

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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