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When we talk about intelligence, we tend to think about what system we can use to measure it. When we talk about how intelligent a person is, we may think about how hig

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

h his/her IQ level is. IQ is the Intelligence Quotient of a person derived from the equation of mental age over chronological age. It is said that the higher a person’s

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

cognitive capability is, in relation to his number of years lived, the more intelligent he is.

So we tend to think that people with higher IQ are more intelligent tha

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

n people with lower IQ. Ok, but if you take a group of people with perfectly functioning brains and with normal psychological makeup, are the ones with higher IQ really

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

always considered to be more intelligent than the rest?

Answer is yes and no.

If you take higher IQ as a simple definition that so and so is more intelligent than an

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

other. Then the answer is NO.

If you take higher IQ to mean that a person has certain higher cognitive capabilities than others then the answer is Yes.

You see, IQ do

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

es not measure all of a person’s intelligence. It only measures part of it. We all know that there are three faculties that an IQ test is testing a person in. There are

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

seven types of intelligence and IQ measures only three of the seven.

Psychologist Howard Gardner identified the following distinct types of intelligence. They are list

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ed here with respect to gifted / talented children.

1. Linguistic
Children with this kind of intelligence enjoy writing, reading, telling stories or doing crosswo

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

rd puzzles.

2. Logical-Mathematical
Children with lots of logical intelligence are interested in patterns, categories and relationships. They are drawn to arithme

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

tic problems, strategy games and experiments.

3. Bodily-Kinesthetic
These kids process knowledge through bodily sensations. They are often athletic, dancers or go

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

od at crafts such as sewing or woodworking.

4. Spatial
These children think in images and pictures. They may be fascinated with mazes or jigsaw puzzles, or spend

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

free time drawing, building with Leggos or daydreaming.

5. Musical
Musical children are always singing or drumming to themselves. They are usually quite aware of

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

sounds others may miss. These kids are often discriminating listeners.

6. Interpersonal
Children who are leaders among their peers, who are good at communicating

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

nd who seem to understand others’ feelings and motives possess interpersonal intelligence.

7. Intrapersonal
These children may be shy. They are very aware of thei

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

r own feelings and are self-motivated.

IQ test measures a person’s Linguistic, Logical-Mathematical and Spatial Intelligence. The first two are left-brained and the th

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ird is right-brained. But there are still four other areas of intelligence than IQ does not measure. Areas in which people can be geniuses in as well.

We cannot use IQ

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

alone as a basis to compare the intelligence of people with one another. In fact, some people are more intelligent than others who may have higher IQ than them! How is

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

that so? Simply because, there is a difference between having certain enhanced cognitive capabilities and using these capabilities in combination and harmony with the

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

rest of your mind in an integrated and holistic way.

There is a difference between using your brain in a partial way, and using it in a complete and well connected way

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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The wind had gone out of my sails. I had a sinking feeling, like I was going down for the third time . . . and I couldn’t even recall the first two. Yet, each time someone asked me, “How’s business,” I would reply, “Good.” It’s kind of a natural reply to a rhetorical question. No one really expects an answer. No one wants to hear bad news, or so you would think.

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