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We all dream as we sleep, during discrete stages called REM (Rapid Eye Movement). Some dreams also occur in non-REM. Our longest REM phase is 1 1/2 hours for most peop

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

le, shortly before they awake. This is why we so often have recall of a vivid dream when the alarm clock goes off. The difficulty is being able to recall dreams. These

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

dreams contain immensely important information about how the psyche is operating.

One may think of a dream as a movie about the way we are living our lives, a commen

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

tary, often in a disjointed way, that tells us about our conscious world. Whenever possible, we should record and interpret our dreams. But why? There are a number of

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

reasons : Dreams provide the most direct access to unconscious material, giving us access to the inner world of symbols or archetypal images. The contents of the uncon

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

scious compensate/complement our conscious attitudes and beliefs, giving us feedback on our lived experiences, by telling the situation of the psyche ‘as it is’. Drea

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ms also may have a healing quality. Can you recall a time when a dream left you feeling peaceful and certain about a problem you were dealing with in your life?

Carl

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

Jung saw dreams as ‘snapshots’ of our life as it is at that very moment. But how does one attempt a Jungian dream interpretation? Central to Jung’s approach was that t

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

he interpretation must fit the dreamer, so if someone helps you work through a dream, the final result must fit you and not someone else. Here are some key ideas that

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

can help you achieve an interpretation. First keep a dream journal next to your bed. Use the journal only for writing down your dreams, and nothing else. When you reca

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ll a dream, write it down just as you remember it, don’t edit it, or change your grammar or spelling. Often we will have strange new words in dreams – write these down

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

because they are valuable just as they are. Second, write down how you felt inside the dream – was I happy, anxious, sad or scared etc. Then write down how you feel n

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ow. Third -write a short paragraph on what your conscious life involved over the past few days, what attitudes you are using, what challenges you are facing, i.e. what

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

is troubling you over the past few days. Fourth -Underline the figures and objects in the dream text and then write a few brief associations to these. Identify the ob

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

jects/figures that have strong symbolic meaning to you. Amplify (or flesh out) these objects/figures using your own ideas. Fifth –work out the parts or the structure

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

of the dream.

Like all movies, dreams often have beginnings, middles, and ends. Jung used specific names for the four parts of the dream : EXPOSITION : who is there,

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

where did it happen? DEVELOPMENT : How does the dream progress? What happens to the figures/objects in the dream? CRISIS : What happens in the critical moment of the d

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ream? LYSIS : How does the dream end? How is a solution presented?

Finally, ask yourself what is the dream speaking about and does this relate to a conscious attitude

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

or issue. This is the last stage of the interpretation – when you know what the dream is commenting on (your conscious attitude) and know how you felt in the dream, a

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

nd know what each of the dream symbols means to you, you can develop a sense of what the dream is saying about you, and may even be suggesting what you need to change.

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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One thing is to defend convictions and another is to pursue such convictions when it is clear that they are wrong. Why do you think they put erasers on penicls?

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