Advice Pool - Health and Fitness

Full lips have long been considered a major beauty asset. Fortunately, even those with thin lips can now enhance the shape and fullness of

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

their lips thanks to lip augmentation. In this procedure, either implant or fillers are used to add volume and shape to the lips, creatin

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

g a fuller, more sensual looking mouth.

Before you decide if lip augmentation is right for you, there are a number of different factors t

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

at you need to consider. Start by learning all that you can about the procedure itself. Next, you need to determine if you are a good cand

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

idate for this cosmetic procedure. Finally, it is essential to understand the possible risks and limitations of this technique. By becomin

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

a well informed cosmetic surgery consumer, you will be better able to make the most of your lip augmentation experience.

Preparing for t

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

he Lip Augmentation Procedure

Before the procedure begins, your doctor will start with an initial consultation to determine if you are a

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

good candidate for lip augmentation. Your doctor will take a thorough medical history and will also discuss your goals and expectations. M

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ny surgeons recommend bringing example pictures with you in order to point out what you like as well as what you do not like. Your doctor

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

will then be able to tell you if your goals are realistic and achievable.

Once you have decided to move forward with the lip augmentation

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

procedure, your doctor will provide you with a list of specific instructions for pre-surgical preparation. These steps include avoiding sm

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

oking, over-the-counter drugs and arranging soft-food meals for the days immediately following your surgery.

Types of Lip Augmentation

T

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

he exact procedure will vary depending on the type of lip augmentation you have chosen. There are three basic types of lip surgery procedu

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

es: injections, surgical implants and fat transfer. In the injection method, substances such as fat or collagen will be injected into the

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

lip in order to improve the shape and increase the fullness of the lips. While this procedure is the least invasive type of lip augmentati

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

n, the results typically last no more than three or four months.

In the surgical implant method, tiny incisions will be made at the corne

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

rs or inside of the mouth. Next, the lip implants will be inserted through these incisions. Unlike injections, lip implants are a long las

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ting lip enhancement solution.

The fat transfer method is a relatively new lip augmentation technique. The surgeon starts by taking fat t

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

at has been removed from another part of the body with liposuction. Then, this fat is inserted into the lips in order to achieve additiona

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

l fullness. Because the implanted fat comes from your own body, it is less likely to be rejected and produces very natural looking results

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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