Advice Pool - Health and Fitness

For many people acne is considered a problem that mainly affects the face. The main reason for this assum

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ption is that this is where it is most visible. Unfortunately this is not the case as acne can also affec

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

t other parts of the body like the neck, shoulders, buttocks and the back. Such areas can be quite painfu

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

when one is afflicted with acne in those parts of the body. This often leads to the belief that thereis

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

no treatment of body acne available.

The main culprits that lead to acne are dead skin cells, oil and to

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ins which block the skin pores leading to inflammation, swelling and acne pimples.

Hormonal imbalances c

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

an also severely increase acne breakouts. Stress is another factor that can lead to acne breakouts becaus

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

it compromises the endocrinal and immune systems. Sever cases of acne can cause acne lesions and take a

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

longer time to heal which unfortunately makes the skin even more susceptible to further acne problems in

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

he future.

Scarring can result from body acne much the same way that facial acne can. Scarring from body

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

acne can actually be more pronounced than facial acne. This is due to the fact that acne on those parts

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

of the body are more prone to irritation from daily activities.

While searching for the right treatment

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

or body acne there are a couple of things that can be done to lessen the possible severity of acne on you

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

r body.

1. Do not wear jewelry that might irritate the skin in affected areas

2. Don't wear tight cloth

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ng that can further aggravate the area of the skin which is affected with acne

3. To reduce the possibil

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ity of re-infection keep everyday cleaning items like towels and bedding items as well as clothing clean.

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

4. Avoid carrying backpacks and items with straps on the shoulder if that part of the body is affected w

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ith acne.

5. After a shower or bath pat the body down with a towel rather than rubbing

One of the best

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

robable ways for the treatment of body acne is to eliminate toxins which may have built up in the body. T

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

his approach coupled with a healthy diet can boost the immune system and help prevent acne from occurring

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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