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Aromatherapy is one of the safest therapies if used under the directions of a qualified Physician. Essential oils are natural plant extracts derived from specific plant species

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

using steam distillation, expression or chemical extraction.

Special attention should be paid while applying essential oil. Some essential oils should be avoided at certain tim

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

es and others should be handled with care. Here a few safety tips are given on the use of aromatherapy oils.

Be very conscious in case of undiluted essential oil. Never put it

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

n your skin in an undiluted condition. Always dilute essential oils with carrier oils such as almond or baby oil. If you make your own oils by infusing plant matter in carrier o

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

il, the resulting oil will be weak enough to use on the skin. If you are suffering from epilepsy or have sensitive skin, are pregnant or are using homeopathic remedies or taking

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

some other prescribed medication or have a heart problem, always consult with your general physician before using any essential oil. People with epilepsy should not apply any pr

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

oduct with citrus oils to their skin if you are going out in the sun. The essential citrus oils can cause burning and reddening of the skin.

Do not take essential oils orally.

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

If planning to work with oil you have not used before, do a small skin test on your arm. Avoid it if there is any irritation. Avoid eucalyptus, fennel, hyssop, sage, pennyroyal,

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

juniper, tansy, thuja, turpentine, and rosemary, as these oils may cause seizures. People with high blood pressure should avoid rosemary, sage and thyme.

Asthmatics should avoi

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

d direct inhalation of essential oils, as this could trigger an attack. Avoid the contact of essential oils with eyes. Essential oils are very irritating to the eyes so it shou

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

d not be applied near them. Also avoid touching the eyes with your hands that may still have traces of oil. It is to be remembered that one should never burn pure oil in the oil

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

burner put water in the reservoir and add a few drops of oil to the water. Keep oils stored in a cool, dark place or in the fridge. Some organic essential oils are very toxic a

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

nd should not be used at all, yet are still sold. Always check the safety of any oil product before you buy it. For the most part, you can use commonly available essential oils

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

uch as lavender with confidence.

Always keep essential oils out of the reach of children. It is preferable to put it in a locked cupboard or locked carry case. If a child does

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

accidentally ingest any essential oil do not encourage vomiting, let them drink one glass of cold water and seek immediate and urgent medical advice.

The great benefit with aro

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

atherapy is that most of them are very useful. Therapeutic herbs are those that smell good so it is not too hard to avoid the ones that smell bad and may be toxic!

Many oils ar

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

e referable for babies and children under 12 years of age. For those oils, which can be used for babies and small children, is advisable to dilute with other resources.

Any ess

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ential oil can cause dermatitis and sensitization, especially when used repeatedly. Avoid this by using only very small amounts of the oil at any one time. You should also pract

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ce substituting the oils from time to time rather than using the same oils every day. When choosing essential oils, always check the Latin or botanical names to be sure you are

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

using the right oil. Many essential oils may have the same common name but may exert different functions. There are also many essential oils that have more than one common name

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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