Advice Pool - Health and Fitness

Enzymes are perhaps the most important nutrients in your body. They catalyze every single reaction that allows you to live: think, move, breathe, etc. Enzymes are contained in raw food and

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

are killed by heat. Conserving and adding to your enzyme store will help you to live healthier and longer -- as well as being key to migraine headache prevention.

Why Are Enzymes So Im

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ortant?

Enzymes are critical to life -- you die when they are gone -- and you apparently have a limited capacity to make them. Research indicates that you are born with an 'enzyme pote

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

tial' -- only a certain amount of enzymes can be manufactured by your body. It seems that Nature intended you to conserve and add to your enzyme store by careful choice of what you eat. How

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ever, for many reasons this doesn't happen.

What Are Enzymes?

Enzymes are very large proteins that catalyze (speed up) every chemical reaction in your body. Enzymes make possible e

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

erything from cellular division to brain activity. The quality of your life is in direct proportion to your store of enzymes.

What Kinds of Enzymes Are There?

Digestive Enzymes<

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

b>: About two dozen types, largely produced by the pancreas. They break food down into the small, readily absorbable particles required by your body for energy, repair, etc.

Metabolic E

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

nzymes: Hundreds and hundreds of types, and found in all body tissues. Normally they run all body processes except digestion.

Dietary Enzymes: The enzymes contained in raw food.

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

Why Is Raw Food Important?

Raw food contains enzymes specifically created for digesting itself. These enzymes begin the process while the food is in your mouth, being chewed. The e

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

zymes continue the process while the food rests in the upper (cardiac) portion of your stomach.

Why Is This Valuable?

Because raw food brings along its own enzymes, it takes the bu

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

den from your body's digestive enzymes (as well as from your metabolic enzymes.) Your enzyme storehouse isn't depleted as rapidly as it would be if IT had to supply all of the digestive pow

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

er for everything you ate.

What About Cooked Food?

When you cook food, the enzymes it contains are destroyed. In order to digest cooked food, your body has to manufacture and secre

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

e 100% of the enzymes required. Depending on the type and amount of cooked food you eat, your body may not be able to meet the demand for digestive enzymes. When that happens, it wil

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

take metabolic enzymes from the tissues of your body and transform them into digestive enzymes.

Why Is This a Problem?

If metabolic enzymes are diverted to help digest food, they

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

are not doing their primary work -- regulating the heart or the brain or the rest of the body. In effect, you have set up a competition for enzymes among the various organs and tissues of y

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ur body. Some of the problems caused by insufficient metabolic enzymes: inflammation, decreased ability to heal -- and migraines.

Incompletely digested food can produce toxins in th

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

bowel that seep out and get into the blood -- another route by which they can cause headaches.

What happens when the supply of metabolic enzymes also becomes exhausted? The chemical proce

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

sses cannot run fast enough to provide enough energy to your cells. 'When you lose your last enzymes, you die.'

What Can You Do?

Eat as many foods as you can in their raw state, so

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

you use their dietary enzymes to predigest the food and put less of a strain on your digestive and metabolic enzymes. Eat lots of enzyme-rich foods.

Eat organic foods. Organic compost has

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

igh levels of enzymes so that organic foods have more concentrated enzymes than food grown conventionally. And organic foods do not contain pesticides and other toxins that poison your body

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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Advice Pool - Migraine Headache Prevention- Part 4 of 5

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