Advice Pool - Health and Fitness

A migraine headache is a symptom. The pain is a sign that something is seriously wrong. You have a choice: you can choose prevention -- find the cause and make changes

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

in your life. Or you can look for the fastest way to get rid of the pain (which will come back again and again.)

What Does Your Body Need?

Every cell in your b

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ody needs three simple things: Provide it with the right raw materials. Let it do its work -- producing energy, synthesizing essential building blocks, repairing tissue

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

s, organs, etc. Help it to get rid of any wastes.

When you interfere with any of these steps, something that needs to get done doesn’t get done. Things go wrong. You f

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ind out when your body gives you a signal -- like a migraine.

Why Don’t You Give Your Body What It Needs?

There are lots of reasons or excuses: You’re working

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

hard, you’re under a lot of stress. Your time isn’t your own. You don’t have time to exercise. You don’t get enough sleep. You aren’t able to eat at the same time every

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

day. You have to grab something to eat wherever you can. You’re so rushed you can’t even sit down, you have to eat on the run. You don’t have time to be picky; you eat

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

whatever is at hand. You don’t think about nutrients; you grab something to fill your stomach, raise your blood sugar, or give you a caffeine jolt.

The Body Has It

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

s Limits.

Sometimes it’s amazing that your body continues to function as well as it does, considering how you neglect it. But that’s a function of the body; it com

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

pensates. It keeps looking for ways to keep you going, in spite of what you throw at it (or in it). However, one day the body reaches a point where it can’t compensate

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

any more. A serious illness or condition develops, one that you may not be able to bounce back from.

Migraine -- A Sign of Serious Neglect

Most people treat a

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

migraine as if it is an inconvenience (albeit an excruciating inconvenience) that needs to be dispensed with as soon as possible. All they want to do is stop the headac

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

he, whatever it takes. They pop a pill: when they get the migraine, or maybe every day so they don’t get a migraine. They think the important thing is to get back to w

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

hat they were doing before that terrible pain so rudely interrupted them.

But popping a pill is not prevention; it is avoidance. A migraine is a symptom of something s

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

erious; your body is telling you to take action; not to ignore it.

So What Should You Do?

No one who gets a migraine would minimize the importance of being f

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ree of pain. But if your only objective is to stop the pain, you are ignoring what is causing it. You may get rid of it today, but it will come back tomorrow.

There ar

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

e things that your body needs, and things that it needs to avoid. Each of the next four articles discusses a major factor in migraine headache prevention.

As you read

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

these articles, remember to keep things simple. Don’t try to change all your habits at one time. It’s too complicated -- and too discouraging when you realize it can’t

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

be done.

Choose one goal at a time -- something that is important to you. When your motivation is internal, your focus and your energy are greater than when you’re d

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

oing something because someone else said it was important.

And remember that your body ‘wants’ to be healthy. It will work with you; you may be surprised just how much

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

HTTP = HTML link (for blogs, profiles,phorums):
<a href="http://www.advicepool.org.ua/article/226243/advicepool-Migraine-Headache-Prevention-Part-1-of-5.html">Migraine Headache Prevention: Part 1 of 5</a>

BB link (for phorums):
[url=http://www.advicepool.org.ua/article/226243/advicepool-Migraine-Headache-Prevention-Part-1-of-5.html]Migraine Headache Prevention: Part 1 of 5[/url]

Any business activity you might wish to pursue will have either a closed end or an open time commitment associated with it. This is illustrated and discussed by comparing making money with paid online surveys versus making money through an MLM program.

If you went to a school like mine, these tables were drilled into you rote fashion until you can quote any multiplication of any two numbers from 1 to 12. If you didn't learn them this way, or your are at school and you need to learn them, here are some tricks that you can use instead of having to remember them.

Tags

Links

Advice Pool - Migraine Headache Prevention: Part 1 of 5

Related Articles: