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  • Advice Pool - Lighting Therapies to Cure Winter Depression

    SAD (Seasonal Affective Disorder) also defined as winter depression, is a serious condition that has as a cause the lack of bright light during the wint
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    er days. No wonder that this form of depression is treated with light therapy. The incidence of SAD is higher in the northern regions of the Globe, du
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    e to their long winter nights. Statistically women are more affected than men are. The illness has serious repercussions on the general well being of
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    he patient; hormonal disorders (including worsened PMS symptoms for women), weight gain and tendency to overeat and sleeping disorders (oversleep). Yes
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    , you've got that right: SAD is not a typical melancholic depression.

    Because SAD is caused by the absence of light it is only natural that light thera
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    y (as a non-invasive remedy) is preferred to treat this depression. The idea is to replace the amount of light found in normal summer days with artific
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    ial light. The most important is the intensity of the light and not its color spectrum. Therapeutic light is up to 40 times brighter than normal room
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    lights. Many people who suffer from SAD purchase some light boxes (although therapists will argue that inappropriate exposure might lead to secondary e
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    fects: disturbances in the retina, anxiety, etc) and use them while they fulfill normal daily tasks: watching TV, doing laundry, reading or eating. The
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    patients are advised not to stare into the light, but to perform these tasks as if they would be in the presence of ordinary light. The duration of th
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    treatment varies from one week to maximum three weeks and many patients use the light boxes the whole winter, each day. SAD might recur; so many patie
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    nts choose to keep their light boxes for further use.

    If you suffer from SAD and intend to purchase a light box, but you are disturbed by the high pric
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
    e, you should know that some health insurance companies do reimburse for the purchase of the light boxes. It is wise to call your health insurer and as
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    whether there is coverage for such a purchase in your policy or not.

    Just remember: light therapy will just improve your condition, but there are no w
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    arranties that it will cure your depression. As a matter of fact, no antidepressant cures the disorder. When light therapy doesn't relieve your sympto
    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    s you should consult your physician again and ask for treatment alternatives. He or she might recommend medication, in addition to light therapy and no
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    t to replace it.

    If you don't suffer from SAD or any other depression for that matter, but you would still like to bring more light into your home duri
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    ng winter (or maybe just when your windows are not large enough to let in the proper amount of natural light), you could always purchase a light box mad
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    of high power LEDs. Compared to the white fluorescent light boxes, LED light boxes have the advantage of reducing energy costs while emitting light in
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    the same brightness. Many such devices are cheaper than their fluorescent counterparts and if you don't need bright light, you can always dim the LEDs


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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