Advice Pool - Health and Fitness

If you are suffering from diabetes and you have started to take insulin therapy then it is possible for you to gain a little wei

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ght. Usually, people gain about 1-3 pounds of weight when the insulin starts to control of the blood glucose level. While diabet

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

s weight gain is more commonly noticed in women than men, in certain situations it is difficult to forecast who will gain weight

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

Weight gain maybe caused as a direct complication resulting from diabetes itself or the medicines taken to treat other complica

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ions like antipsychotics.

There are many causes behind weight gain during insulin therapy. One reason is that when you take to

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

nsulin therapy, your blood sugar level comes under control, and when insulin controls blood sugar, then your metabolism may begi

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

to fall down. The downside of insulin therapy is that the additional weight that you gain as a result of insulin therapy can ac

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

tually increase your cells' resistance to insulin, which means you may need to get even more medications to tackle the problem.

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

o in a way, diabetes weight gain can actually nullify the effects of insulin therapy, creating a vicious cycle of increased weig

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

t gain and insulin resistance.

I know you might be thinking that: What if I reduce the intake of insulin? Wait before you do th

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

t! There are some people who think that by reducing insulin intake they will be able to lose weight. This perception is obviousl

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

wrong. Stopping or reducing insulin therapy doesn't mean that you will lose weight. On the contrary, if you don't take insulin

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

njections regularly, you are likely to suffer from several complications of diabetes.

I know you are now feeling confused. But

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

et me tell you, there is no need to get confused, because there are ways to get out of this mess. The least you can do is to vis

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

it your local dietician. Your dietician will be able to create a perfect meal plan for you which will provide you with good nutr

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

tion while helping you in controlling diabetes. The next thing you should do is to visit an expert exercise coach and he will he

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

p you create a good workout schedule that will improve your health as well as help you lose weight. Once you lose weight, it is

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

nly a matter of time before you see diabetes vanish completely!

I have told people time and gain that the best remedy for diabe

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

es is to have a healthy diet and regular exercises. I have even written a lot of articles on how to create perfect diet and exe

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

cise plans for diabetics. If you want to know more about diabetes weight gain, simply click on the link in my resource box below

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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