Advice Pool - Health and Fitness

If you want to avert diabetes-related problems, you should see to it that your blood lipids never go out of their normal target

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

range. If your blood lipids go out of normal range, you may suffer from heart diseases and stroke. The best way to keep your blo

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

od lipids within control is to change your lifestyle, take proper diet for diabetes high cholesterol, and take appropriate medic

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ations, more of which will be revealed in this article.

First of all, let me tell you a little about blood lipids and their fun

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ctions.

There are in fact, several types of blood lipids in our body.

1. LDL or the bad cholesterol- The job of this lipid is

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

to block or narrow down your blood vessels. If your blood vessels become too narrow for blood to pass, you may suffer from heart

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

attacks. Keeping this lipid within the normal target range is the best way to protect yourself from heart-related problems.

2.

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

HDL cholesterol or the good cholesterol: This is kind of antidote to the bad cholesterol. While the job of bad cholesterol is t

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

o block your blood vessels, the job of good cholesterol is to remove the blockades from the blood vessels so that blood can flow

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

easily and smoothly.

3. Triglycerides- This is yet another type of cholesterol that is very harmful for your body. Like the ba

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

cholesterol, the presence of too much of this cholesterol can lead to heart attacks and strokes.

A good way to know whether yo

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

ur blood lipids are within normal range or out of target is to have a blood sugar test. In fact, you should have a blood sugar t

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

est at least once in a year, if not more.

Do you how diabetes can trigger a heart attack?

Diabetic patients generally have a l

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ow amount of good cholesterol and a high amount of Triglycerides in their bodies. This creates problems. Worse- these people usu

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ally have small amounts of dense bad cholesterol which block the blood circulation. All these create the perfect environment for

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

a heart attack. But of course all is not lost. You can still take charge of your life and control your blood lipids if you want

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

to. You can take certain steps which will help you lower the amount of bad cholesterol and increase the level of good cholester

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ol. You can take the appropriate diet for diabetes high cholesterol as recommended by your doctor. In this way you will be able

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

to avert any heart related problems.

In the second part of this article I will discuss the kind of treatments you should take i

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

n order to control of blood lipids. To access the second part of this article, simply click on the link in my resource box below

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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