Advice Pool - Health and Fitness

Diabetes is generally found in overweight people. Diabetes and exercise are complementary, since exercise lowers s

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ugar levels and reduces the need for insulin. Exercise also protects the body against heart attacks and strokes, s

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

rengthens bones, tones and strengthens muscles, improves how you feel, relieves stress, improves your quality of s

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

leep, and the quality of your life. While you may think the list of benefits might be applicable to anyone, it is

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ven more applicable to diabetes. Each of the benefits may require a reduction in medication. Lowering sugar levels

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

and reducing the need for insulin can bring your sugar levels down enough that you may not need medication at all.

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

By lowering your risk of heart attacks and strokes, you may also not need medication for cholesterol or high bloo

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

pressure, as your body will be fit and healthy.

Once you start losing weight, muscle and joint pain will go away

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

, and exercising will become easier. It’s always difficult to start, especially if movement is uncomfortable. Walk

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

ng as little as 30 minutes a day can have a positive effect. Walking for a few hours once or twice a week will not

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

only cause pain because your body is not used to the exercise, but it doesn’t count toward regular diabetes and ex

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

ercise routine. Swimming is a wonderful form of low or no impact exercise that is perfect for people who are not u

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ed to the exertion of walking or jogging. A half-hour in the pool, with some kicking or swimming, or even water ae

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

robics, can be very beneficial. You may find that starting in the shallow end with some minor aerobics will be so

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

njoyable that you want to do more. Year-round swimming pools are no available at many health clubs or physical the

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

apy centers, and health insurance may pay if it is for a diagnosed medical condition. It is worth investigating th

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

e possibility with your health insurance provider.

Once you are walking and exercising, you’ll be sleeping and th

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

nking better. Colors will seem brighter, food will taste better, and you will probably find you are happier. Exerc

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ise releases many chemicals in your body that make you feel better, and feeling better about yourself will make yo

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

want to experience the change. You can control your diabetes and exercise your right to a happier, healthier life

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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