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  • Advice Pool - Diabetes Information That Everyone Should Know

    Diabetes is one of the common metabolic diseases that occur due to defects in the carbohydrate metabolism in the body. It affects approximately 17 million people (ab
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    out 8% of the population) in the United States. In addition, an estimated additional 12 million people in the United States have diabetes and don't even know it.

    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    >Causes of Diabetes

    • Excess intake of oil and sugar
    • Hereditary and genetics factors also leads to diabetes
    • Increased cholesterol level
    • Ove
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    r weight
    • Stress
    • No physical activities

    Symptoms of Diabetes

    • Frequent urination
    • Excessive hunger and thirst
    • Problems of back a
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    nd joint pain
    • Tiredness or general weakness
    • Loss of weight
    • Long time for healing of wounds

    Complications of Diabetes

    • Diabetes may lea
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    d to blindness, kidney failure, and nerve damage.
    • It is also an important factor in accelerating the hardening and narrowing of the arteries (atherosclerosis)
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    , leading to strokes, coronary heart disease, and other large blood vessel diseases.
    • It is also the leading cause of blindness in United States. It can cause
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    a number of eye problems, some of which can lead to blindness if not addressed
    • It also increases the risk of gum disease and tooth loss
    • Diabetic patien
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    ts also suffer from impotence or erectile dysfunction.

    Do’s and Don’t for Diabetes

    • Avoid all kinds of sugary and sweet foods.
    • Eat bitter melon herb
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    s either in powdered form (powder of bitter melon seeds) or cooked vegetables. It is very beneficial in the treatment of diabetes. You can also drink it in the form
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    of soup.
    • Do not take starchy food products, as they are not easily digestible.
    • Also avoid coffee, sugar, refined flour and alcohol.
    • Include onio
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    n, sprouts, beans, garlic, tomatoes in the diet as it helps in lowering the sugar level in the blood.
    • Do not eat junk food and oily food as this will control
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
    your level of cholesterol, lowers your blood pressure level, and diabetes

    Home Treatments for Diabetes

    • Gooseberry helps to cure diabetes and brings the bl
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    ood sugar level to normal.
    • Curry leaves also helps in controlling body weight and also diabetes. Chewing (8-10) curry leaves in an empty stomach to bring suga
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    r level in urine and blood to normal.
    • Dry the leaves of mango tree and make its powder in a grinder. Mix the dry powder (1 teaspoon) of mango leaves in a glas
    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    s of water and drink it everyday to cure diabetes.
    • Soak few fenugreek seeds in water and keep them overnight. Have these softened seeds in the morning.
    •
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    Garlic contains allicin, which works at reducing the sugar level in the blood. It also brings about the disintegration of cholesterol in the body.
    • Jamun has
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    also specific action on the pancreas, which controls the conversion of starch to sugar. The seeds of the fruit have better effects than the pulp.


    Disclaimer: Th
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    is article is not meant to provide health advice and is for general information only. Always seek the insights of a qualified health professional before embarking on
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    any health program.

    Copyright © Nick Mutt, All Rights Reserved. If you want to use this article on your website or in your ezine, make all the urls (links) active.


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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