Advice Pool - Health and Fitness

The amount of sugar in our body is sometime known as blood glucose level. When foods are eaten, th

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

e body will break it down into the simplest form, namely glucose. Glucose is the fuel for our body

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

where it is the primary source of energy for the cells. The cell extract glucose from the blood st

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ream by using insulin. Diabetes Type I occurs when the body loses its ability to produce insulin m

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

king the extraction of glucose from the blood stream impossible. As a result the sugar content in

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

he blood increases.

The symptoms for diabetes type 1 may vary for each individual, but these are

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

the more common symptoms.

Often diabetic type 1 occurs without any signs or symptoms.

- Sugar co

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

tent are higher than the normal blood sugar content
- The urine is laced with sugar
- Dr

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

inks unusual amount of water
- Urinates frequently
- Lose weight even though frequently

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

eels hungry
- Eyesight becomes blurry
- Feeling nauseous
- Feels lethargic and weak

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

br> - Mood swings

While there are no cure for diabetes, treating it and controlling diabetes wil

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

l further aggravate the problem to other serious health problems such as heart risk and stroke. To

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

minimize other health risks, it is important that the blood sugar level are maintained to normal a

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

s close as possible.

The steps listed below are some of the steps that can be taken to control di

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

betes type 1:
- Never skip insulin as prescribe
- Eat healthy by watching the amount of

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

arbohydrate you take and follow diabetic diet plan as strictly as possible.
- Watch your bloo

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

d sugar content without fail
- Get physical exercise and do it regularly

Treating diabetes w

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ll help the body maintains as close to normal its blood sugar content. Diabetes type 1 are lifelon

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

g illness where there are no cure, as such the treatments is also lifelong. To remain healthy, dia

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

etics must observe lifelong treatments through proper eating and exercising throughout their lives

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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