Advice Pool - Health and Fitness

How does exercise help diabetes?

Exercise is a great way to help control weight and it also lowers the blood sugar level. It also lowers a person’s risk of heart disease - a condition that is very common in people who have diabetes. Exerci

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

se can also help you feel better about yourself and increase your overall health.

What kind of exercises to be done?

There are no specific exercises for one to do. Choose any cardio exercise (walking, running, cycling, aerobics, skating,

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

arm-ups and cool-downs, tennis, etc.) - anything that increases the heart rate. Aerobic exercise strengthens the heart and keeps the exerciser’s muscles warm. Strength training builds stamina, while improving both joints and muscles. Warm

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ups and cool-downs are essential for the safety of the exerciser.

No matter what kind of exercise one does, make sure to warm up before starting, and cool down when done. To warm up, spend 5 to 10 minutes doing a low-intensity exercise suc

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

as walking. Then gently stretch for another five to ten minutes. Repeat these steps after exercising to cool down.

When you start an exercise program, go slowly. Gradually increase the intensity and length of the workout as one gradually

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

gets more fit.

Consult a doctor about what kind of exercise is right for you, depending on whether one has any other health problems.

1. Aerobic exercise -

Aerobic exercise helps increase heart rate, as well as breathing rate. This makes

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

one breathe more deeply and also makes the heart work harder. It is best to aim for a total of about 30 minutes a day, at least 5 days a week. Here are some examples of aerobic exercises: - Take a brisk walk either outside or on a treadmi

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

l

- Dance classes

- Swimming

- Jogging

- Roller-skating

- Tennis or badminton

- Indoor stationary bicycle

2. Strength training -

Strength training, done several times a week, helps build strong bones and muscles. Some ways to do it:

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

- Join a gym to do strength training with weights.

- Lift light weights at home

3. Flexibility exercises -

Flexibility exercises, also called stretching, helps keep joints flexible and reduces the chances of injury during other activiti

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

es. Gentle stretching for 5 to 10 minutes helps the body to warm up, as well as get ready for aerobic activities.

4. Be on the move throughout the day -

Being active helps burns calories. The more you move around, the more energy one will

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

have.
« Walk instead of driving whenever possible.
« Take the stairs instead of the elevator
« Work in the garden or do some housecleaning every day
« Walk to the market; park your car ? kilometer before the market.

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

Are there any risks associated with exercising for people with diabetes?

There are some mild risks, but the benefits far outweigh the risks. So, its necessary to moderately exercise daily the right way.

Exercise changes the way in which

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

the body reacts to insulin. Regular and strenuous exercise makes the body more sensitive to insulin, and thus, the blood sugar level may suddenly get too low after exercising. Therefore, it is important to check the blood sugar level befo

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

re and after exercising, and follow the doctor’s advice as suggested for low blood sugar.

If the blood sugar level is too low or too high right before one starts exercising, it is better to wait until the level improves, and normalizes.

I

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

is also important to keep a check on blood sugar level if exercising in extreme hot or cold conditions, because temperature affects how the body absorbs insulin.

Should one drink plenty of fluids during exercising?

Yes. While exercising,

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

our body uses more fluid to keep the body temperature cool. Therefore, by the time one feels thirsty, he may already be getting dehydrated. Dehydration can seriously affect the blood sugar level in the body. Drink plenty of fluids, water be

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ore, during and after exercise. What safety tips to follow while exercising?

Exercise can affect and lower the blood sugar level, so pay attention to possible warning signs during workout such as:

- Sudden change in heartbeat

- if one

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

starts sweating more

- feels shaky, anxious or hungry

- feeling weak or dizzy

If you feel this way, stop exercising and check out on a doctor. It might be hypoglycemia or low blood sugar. It is normally recommended to keep candy, glucose

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

biscuits or juice nearby to treat hypoglycemia. Exercise tips for people with diabetes:

- Talk to the doctor about the right exercise for you.
- Check blood sugar level before and after exercising.
- Wear the proper shoes and

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ocks, so as to avoid infection and blisters.
- Drink plenty of fluid before, during and after exercising.
- Warm up before exercising and cool down afterward.
- Have some juice handy in case blood sugar level drops too low

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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I don't want to put you off becoming a pro, but there are a few things you should ask yourself. Firstly is it worth it? Can you push yourself to the extreme and still be courteous to customers who are having a bad day while you are having one yourself. If you can be understanding and kind while you yourself are feeling like hell then tick yourself one box. I found that serving time as a sales assistant helped me a lot in this regard.

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