Advice Pool - Health and Fitness

Dr. Nicholas Perricone, noted beauty expert, recently stated that a specific trace mineral, known as NBC (niacin-bo

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

und chromium) has substantial benefits for Type 2 diabetics. These benefits have been extensively documented in va

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ious clinical studies at Georgetown, Harvard and other well-regarded medical institutions, providing hope for pre-d

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

abetic and Type 2 sufferers.

Chicago, Illinois. January 13, 2007. Dr. Nicholas Perricone, most noted for best-se

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ling beauty-based books such as the Perricone Prescription, has identified a possible trace mineral supplement that

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

helps promote proper insulin function and healthy body weight for Type 2 diabetics.

In his just-published book, 7

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ecrets to Beauty, Health and Longevity, Perricone cites studies conducted at Georgetown University Medical Center,

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

hich substantiate the benefits of NBC (niacin-bound chromium) for those with diabetes.

Among the benefits of this

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

race mineral, Perricone says that it promotes healthy body weight, lean body mass, promotes proper insulin function

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

and healthy cholesterol levels

In addition, he believes that ingestion of this mineral will also extend your life

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ongevity by up to 20%.

Sound too good to be true?

Well it’s for real!

A substantial body of research compiled at

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

Georgetown, Harvard, UC Berkeley, Creighton and other leading medical institutions, on this specific chromium, has

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

een conducted over the last 10 years and clinically documented the power of niacin-bound chromium.

Based on a numb

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

r of factors (most notably the rise of high fructose corn syrup sweeteners that drain the body of system maintenanc

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

chromium), supplementation with this highly bio-available (readily absorbed) chromium offsets the diabetes-inducin

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

impact of these sweeteners.

Niacin-bound chromium, in addition to being the most effective form of chromium suppl

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

mentation, has also been proven to be the safest, the only known chromium version to be verified GRAS (Generally Re

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ognized As Safe), in independent studies.

Perricone has been at the forefront of longevity research, leading accep

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ance for anti-inflammatory solutions.

And his high profile status as a best-selling book author brings welcome att

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ntion to a mineral that has been substantially documented to bring welcome relief to millions of diabetes sufferers

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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