Tags |
|
|
Links |
|
|
Advice Pool - Supplements For Diabetes – What Recent Studies Say?
Diabetes is a chronic condition in which body does not produce or produce less insulin compared to healthy individual or body develops resistance to insulin (body does not respond to insulin).
Most foods that we consu
Most foods that we consu
According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
me finally enter into the blood in form of carbohydrate, fat & protein. From blood, these nutrients enter into cells. Insulin is required for this entry of glucose into cells. Body cells utilize carbohydrate & fat for
; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.
Examples of combination products may in
Examples of combination products may in
nergy & growth.
Because of less insulin or resistance to insulin in diabetes, blood sugar cannot enter into cells & remain in blood resulting in high blood sugar.
Studies have shown that supplements like chromium, al
Because of less insulin or resistance to insulin in diabetes, blood sugar cannot enter into cells & remain in blood resulting in high blood sugar.
Studies have shown that supplements like chromium, al
lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.
pha lipoic acid & vanadium plays an important role in the management of diabetes.
Chromium supplements in diabetes:
Diabetes is associated with low concentrations of chromium in blood, so, an ear
Chromium supplements in diabetes:
Diabetes is associated with low concentrations of chromium in blood, so, an ear
here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
y, long-term addition of chromium to the standard therapy has been recommended in several studies. Some latest clinical reports also support the safety and therapeutic value of chromium supplementation for the manageme
d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.
Combination pro
Combination pro
t of high cholesterol and sugar in subjects with diabetes.
Chromium increases insulin receptor numbers & insulin binding to cells. Since chromium acts by increasing insulin efficiency, so lower amount of insulin is re
Chromium increases insulin receptor numbers & insulin binding to cells. Since chromium acts by increasing insulin efficiency, so lower amount of insulin is re
ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
quired in presence of chromium.
A clinical study published in ‘Diabetes Care. (2006, August)’ has shown that chromium supplementation in subjects with type 2 diabetes significantly improves insulin sensitivity and glu
A clinical study published in ‘Diabetes Care. (2006, August)’ has shown that chromium supplementation in subjects with type 2 diabetes significantly improves insulin sensitivity and glu
easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
ose control. Chromium supplementation also reduced body weight gain and fat accumulation
A latest review article published in Diabetes Technol Ther. 2006 December has mentioned that 13 of 15 clinical studies involving
A latest review article published in Diabetes Technol Ther. 2006 December has mentioned that 13 of 15 clinical studies involving
nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
a total of 1,690 subjects reported significant improvement in at least one outcome of glycemic control. (Glycemic control is a medical term used for blood sugar levels in a person with diabetes) Beneficial effects of c
and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
hromium supplementation included reduced blood glucose, cholesterol, and triglyceride levels and reduced requirements for drugs for diabetes.
Reduction in blood sugar & improvement in insulin sensitivity with chromium
Reduction in blood sugar & improvement in insulin sensitivity with chromium
ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
results in decrease risk for diabetes complications.
Alpha lipoic acid in Diabetes:
Alpha lipoic acid is a powerful antioxidant, which is produced in the body & also present in food. High blood s
Alpha lipoic acid in Diabetes:
Alpha lipoic acid is a powerful antioxidant, which is produced in the body & also present in food. High blood s
ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.
Following aspects would a
Following aspects would a
gar in diabetes increases free radical formation in body, which leads to additional complications of diabetes like atherosclerosis, heart problems, nerve damage & cataract. Antioxidant decreases free radicals in body &
dd to the challenges in developing combination products:
Which markets to tap where the combination products can do fairly well?
Which combination prod
Which markets to tap where the combination products can do fairly well?
Which combination prod
decreases risk of complications.
There are number of publications confirming beneficial effect of lipoic acid in therapy of many diseases, including diabetes, atherosclerosis, degenerative processes in neurons, disea
There are number of publications confirming beneficial effect of lipoic acid in therapy of many diseases, including diabetes, atherosclerosis, degenerative processes in neurons, disea
cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
es of joints,
A recent clinical study on diabetic patients treated with alpha lipoic acid was published in ‘hormones (Athens). 2006 Oct-Dec 5(4)’. The result of the study has proved that short-term oral alpha-lipoic a
A recent clinical study on diabetic patients treated with alpha lipoic acid was published in ‘hormones (Athens). 2006 Oct-Dec 5(4)’. The result of the study has proved that short-term oral alpha-lipoic a
tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
id treatment increases peripheral insulin sensitivity in patients with type 2 diabetes.
Improvement in insulin sensitivity could improve both blood sugar control and cardiovascular risk factors in patients with type 2
Improvement in insulin sensitivity could improve both blood sugar control and cardiovascular risk factors in patients with type 2
t?
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
diabetes.
Peripheral insulin sensitivity gives an idea about how body cells respond to insulin. In diabetes, because of decrease response to insulin by body cells, blood sugar cannot enter into cells causing high blo
Peripheral insulin sensitivity gives an idea about how body cells respond to insulin. In diabetes, because of decrease response to insulin by body cells, blood sugar cannot enter into cells causing high blo
ping new procedures for reviewing their safety, efficacy and quality.
Professional from academic institutions, pharmaceutical industries, health care indust
Professional from academic institutions, pharmaceutical industries, health care indust
d glucose. Alpha lipoic acid enhances glucose uptake by cells in type 2 diabetes.
Diabetic neuropathy or nerve damage is a complication of diabetes. It is a progressive disease, which can cause pain, loss of sensation
Diabetic neuropathy or nerve damage is a complication of diabetes. It is a progressive disease, which can cause pain, loss of sensation
y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
and weakness, in the feet and sometimes in the hands. Studies have shown that alpha lipoic acid is effective in management of diabetic nerve damage called neuropathy and it reduces pain associated with neuropathy.
.
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
rong>Vanadium supplement in diabetes:
Vanadium is a trace mineral required by the body in small quantities. Numerous studies have shown that vanadium has insulin-like effects in liver, skeletal muscle, an
Vanadium is a trace mineral required by the body in small quantities. Numerous studies have shown that vanadium has insulin-like effects in liver, skeletal muscle, an
elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.
Companies that provide selfless information through particip
Companies that provide selfless information through particip
adipose tissue. It may improve glucose control in people with type 2 diabetes.
Along with chromium & alpha lipoic acid, supplement like evening primrose oil, fenugreek & some herbs also help in management of diabetes
Along with chromium & alpha lipoic acid, supplement like evening primrose oil, fenugreek & some herbs also help in management of diabetes
tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products
HTTP = HTML link (for blogs, profiles,phorums):
<a href="http://www.advicepool.org.ua/article/240710/advicepool-Supplements-For-Diabetes--What-Recent-Studies-Say.html">Supplements For Diabetes – What Recent Studies Say?</a>
BB link (for phorums):
[url=http://www.advicepool.org.ua/article/240710/advicepool-Supplements-For-Diabetes--What-Recent-Studies-Say.html]Supplements For Diabetes – What Recent Studies Say?[/url]
Related Articles:
The Terrible Throne of Judgment
Childhood Depression: What to Do if Your Child is Depressed
Bookmark it:
|