Advice Pool - Health and Fitness

A glazed donut and large cup of latte for breakfast; a double cheeseburger, mega-sized order of fries and a 20-ouce soda for lunch; and then

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

a 12-ounce steak and a baked potato drowning in butter and sour cream for dinner. Oh, and don't forget the bag of potato chips and chocolat

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

e bar you had for a snack. Sound like a healthy diet to you? Of course not! But whether we want to admit it many of us do not eat a healthy

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

diet. By changing just a few of your eating habits, however, we can both lower our cholesterol and improve our overall health.

Most people

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

cringe when their doctor tells them they need to start eating a low cholesterol diet. While it is important to cut down on the cholesterol

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

in your diet, you are not limited to eating just twigs and berries. A few minor changes in your diet can drastically cut the cholesterol you

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

consume daily.

Instead of a donut and cup of coffee for breakfast, for instance, start your day with a glass of fruit juice and bowl of c

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ereal. If you want to go more hard core than that, try eating oatmeal or shredded wheat. The high fiber content in these cereals is believed

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

to help lower cholesterol. Other good breakfast choices are fruits or yogurt. These foods give your body the nutrients it needs to keep go

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

ing throughout the day without all the fat and sugar of donuts and such.

Because of our modern job schedules, most of us are forced to grab

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

something quick for lunch. This is why so many people wind up eating fast food for their noonday meal. Fast food is synonymous with unhealt

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

hy food. Since today's population has become more health conscious, however, even fast food restaurants are offering options that are health

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ier than the traditional fare. Instead of a greasy hamburger and fries, choose a cold cut sandwich or a salad. Even better would be to pack

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

a lunch from home which could include fresh fruit, raw vegetables, baked potato chips and a low fat sandwich or entr?e.

Supper is often a

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

challenging meal also because many of us are too worn out from our daily jobs to cook a healthy dinner. Even if you choose to eat out for di

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

nner there are some healthy choices you can make here also. Instead of having a steak, choose grilled chicken or fish. These meats have les

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

s cholesterol than steaks or red meats. Also choose low fat butter and sour cream for your potato. You might even skip the potato altogether

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

in favor of a salad or steamed vegetables.

Small changes can make a big difference when you are trying to lower your cholesterol. Don't try

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

to make changes too quickly, however, as eating habits are difficult to break. Giving up all high fat foods all at once can be a shock to

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

your system. It will be easier if you make small changes over time, you will see results both in your cholesterol and your health in general

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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