Advice Pool - Health and Fitness

Always Use As Directed

Modern medicines include a wide range of drugs that have been developed and are continuously being dev

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

eloped to save lives and make pain more bearable to handle. Before they can be used and marketed in public, they undergo a series of

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

tests and approval for certain, specific uses. Many drugs, such as strong pain killers, are only available when prescribed by a licen

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

sed doctor.

Medical supervision is a must as prescribed medicines can cause harm when not used correctly. When prescribed with these

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

kinds of drugs, you must not put yourself at risk by taking doses that are more than what was prescribed, taking them when they shoul

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

d not be, or combining them with other wrong substances such as alcohol or other drugs.

Commonly Abused Prescription Drugs

A

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ll prescription drugs tend to be harmful when used incorrectly. There, however, three types of drugs that are most commonly abused:

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

i>- Opioid based painkillers such as codeine, Vicodin, Oxycontin, and Demerol.

- Central Nervous System (CNS) depressants suc

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

h as Nembutal, Xanax and Valium, which are usually used to treat conditions like panic attacks, sleep disorders, and stress.

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

- Stimulants like Dexedrine and Ritalin, which are typically used to treat depression, narcolepsy and attention deficit hyperactivity

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

disorder (ADHD)

Harmful Effects

The abuse or misuse of prescription drugs can lead to dangerous reactions and prescript

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

ion addiction. The extended use of opioid based pain killers and CNS depressants over a longer period of time (from 3 weeks to months

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

) can cause physical dependence to these drugs. High doses of these drugs can lead to many problems such as:

- Compulsive, uncont

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

rolled use

- Paranoia

- Dangerously high body temperature

- Slowed or irregular heartbeat

- Coma and

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ven death

- other minor effects such as nausea, vomiting, diarrhea, extreme sweating, and so on, may also set in

Stoppi

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ng the use of prescription use will lead to withdrawal symptoms that might be difficult to handle on your own. The longer the period

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

of use, the more difficult the symptoms can become. Also, the more serious the prescription addiction, the greater the withdrawal sym

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

toms can get. Getting over prescription addiction and going through the series of withdrawal symptoms (especially during the first fe

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

w days) can be unbearable. But having the right treatment method and plan would definitely make things a lot easier to handle. To kno

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

w more about prescription drug addiction, its various types and treatment options, please visit http://www.mypainkilleraddictions.com

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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