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Advice Pool - Dual Diagnosis: Drug Addiction, Alcoholism and Associated Psychiatric Disorder
A person who suffers from alcohol abuse / alcoholism, drug abuse / drug addiction and an emotional/psychiatric problem is said to have a dual diagnosis. To recover fully,
According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
the person will require addiction treatment and psychiatric treatment for both problems.
How Common Is Dual Diagnosis?
Dual diagnosis is a common diagnosis. According
How Common Is Dual Diagnosis?
Dual diagnosis is a common diagnosis. According
; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.
Examples of combination products may in
Examples of combination products may in
to a report published by the Journal of the American Medical Association: * Thirty-seven percent of people with alcohol abuse and fifty-three percent of people with drug
lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.
abuse also have at least one serious mental illness. * Of all people diagnosed as mentally ill, 29 percent suffer from alcohol abuse or drug abuse.
What Type of Mental H
What Type of Mental H
here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
ealth Problems are Seen in People with Dual Diagnosis?
The following psychiatric problems occur in Dual Diagnosis - i.e., in tandem with alcoholism or drug addiction. *
The following psychiatric problems occur in Dual Diagnosis - i.e., in tandem with alcoholism or drug addiction. *
d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.
Combination pro
Combination pro
disorders, such as depression and bipolar disorder. * Anxiety disorders, panic disorder, obsessive-compulsive disorder, and phobias. * Other psychiatric disorders, such a
ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
s schizophrenia and personality disorders.
The following table based on a National Institute of Mental Health study, lists seven major psychiatric disorders and shows ho
The following table based on a National Institute of Mental Health study, lists seven major psychiatric disorders and shows ho
easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
w much each one increases an individual`s risk for drug addiction. Psychiatric Disorder Increased Risk For Substance Abuse Antisocial personality disorder 15.5% Manic epi
nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
sode 14.5 Schizophrenia 10.1 Panic disorder 4.3 Major depressive episode 4.1 Obsessive-compulsive disorder 3.4 Phobias 2.4
Thus, someone suffering from schizophrenia is
Thus, someone suffering from schizophrenia is
and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
at a 10.1 percent higher-than-average risk of alcohol addiction or drug addiction. Someone who is having an episode of major depression is at a 4.1 percent higher-than-av
ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
rage risk of having alcoholism or drug addiction……………….
Drug Addiction, Alcohol Addiction or the Emotional Problem….Which Came First? Often the psychiatric problem devel
Drug Addiction, Alcohol Addiction or the Emotional Problem….Which Came First? Often the psychiatric problem devel
ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.
Following aspects would a
Following aspects would a
ops first. In an attempt to feel calmer, more peppy, or more cheerful, a person with emotional symptoms may drink or use drugs; doctors call this "self-medication." Frequ
dd to the challenges in developing combination products:
Which markets to tap where the combination products can do fairly well?
Which combination prod
Which markets to tap where the combination products can do fairly well?
Which combination prod
ent self-medication may eventually lead to physical or psychological dependency on alcohol or drugs, alcohol addiction or drug addiction. If it does, the person then suff
cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
ers from not just one problem, but two. In adolescents, however, drug or alcohol abuse may merge and continue into adulthood, which may contribute to the development of e
tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
motional difficulties or psychiatric disorders. Dual diagnosis is a complex disorder to diagnose.
If a Person Suffers From Drug Addiction, Alcoholism and a Mental Health
If a Person Suffers From Drug Addiction, Alcoholism and a Mental Health
t?
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
Disorder, Which Should Be Treated First? In a perfect world, both problems should be treated simultaneously. For any substance abuse problem, however, the first step in
ping new procedures for reviewing their safety, efficacy and quality.
Professional from academic institutions, pharmaceutical industries, health care indust
Professional from academic institutions, pharmaceutical industries, health care indust
treatment must be detox - a period of time during which the body is allowed to cleanse itself of alcohol or drugs. Ideally, detox should take place under medical supervis
y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
ion. It can take a few days to a week or more, depending on what substances the person abused and for how long.
Until recently, alcoholics and drug addicts dreaded detox
Until recently, alcoholics and drug addicts dreaded detox
.
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
because it meant a painful and sometimes life-threatening "cold turkey" withdrawal. Now, doctors are able to provide those people with a drug addiction or alcohol addict
elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.
Companies that provide selfless information through particip
Companies that provide selfless information through particip
ion carefully chosen medications while in detox, which can substantially ease withdrawal symptoms. Detox done under medical supervision, is safer for the dually diagnosed
tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products
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