Advice Pool - Health and Fitness

Is your daughter looking thinner than usual? Has she been dieting excessively? Does she visit the bathroom immediately after each meal? Does she seem depressed?

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

These could all be signs of an eating disorder.

There are three eating disorders that affect men and women. In anorexia nervosa people starve themselves because

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

they think they are too fat. Bulimia nervosa involves overeating, then purging immediately after. Binge eating is out-of-control eating, regardless of whether one

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

if hungry or not.

People who are anorexic have an extreme fear of becoming fat. As a result, they starve themselves until they are severely underweight. They als

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

o tend to exercise excessively. Ironically, the word anorexia means loss of appetite. Anorexics, however, have a great deal of hunger that they control. There ar

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

e several techniques that anorexics take to control their eating. They might cut their food into tiny pieces or prepare large meals for other to satisfy their own

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

esire for the food. They also might drink a lot of coffee and tea, use diet pills and smoke to help limit their food intake. Anorexics make excuses to avoid eatin

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

g or hide food to hide the fact that they aren’t eating. Generally women between the ages of 14 and 25 suffer from anorexia, although some men have this eating dis

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

order as well. Many anorexics suffer from bulimia as well.

Bulimics binge eat then purge everything they have eaten. After an episode of binge eating, bulimics f

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

el guilty and ashamed, as well as afraid of gaining weight. This lead to purging. Laxatives are also commonly abused by bulimics. There are several health risks

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

associated with bulimia. Bulimics tend to have more dental problems such as decay and loss of enamel from the extra acid in their mouth from the vomiting. Frequen

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

t purging can also damage the esophagus. Bulimic women who are pregnant have an increased risk of complications. Other health concerns are increased risk of infec

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ions, permanent organ damage, muscle spasms and heart attack.

Binge eating involves eating large amounts of food while feeling out of control and helpless to stop.

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

The difference between binge eating and bulimia is that binge eaters do not purge afterwards or take laxatives. Binge eaters tend to eat faster than usual. They

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

generally eat alone out of shame and embarrassment. They will eat until they are uncomfortably full and they will eat when not hungry at all.

The causes of eati

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

g disorders are not completely understood yet. People who suffer from eating disorders usually feel out of control with some aspect of their lives. Eating is the

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

one thing that can be controlled. Many times, anorexics are starving to be perfect. Controlling their eating helps satisfy that hunger. Bulimics may be out of co

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ntrol while bingeing, but they regain control by purging immediately after. Eating disorders may be brought on as a result of a traumatic experience that leaves a

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

erson feeling helpless and vulnerable.

The first step in overcoming an eating disorder is admitting you have a problem and seeking help. Talk to people about it a

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

nd seek counseling. Eating disorders are harder to overcome the longer they have been present. With the right treatment, it is possible to beat an eating disorder

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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Advice Pool - Eating Disorders - Signs Your Daughter Has One

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