Advice Pool - Health and Fitness

All types of media information advices the population more and more often to eat healthy and exercise daily to avoid obesity and other nutr

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

itional issues. Still, the message seems to be misunderstood as many persons, especially young girls become obsessed with loosing weight an

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

d counting calories; this is the negative part of the media tendencies and leads to the apparition of many eating disorders and dangerous p

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

hysical and emotional consequences.

The most common and vital symptom of anorexia seems to be the irrational and uncontrolled fear of weig

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ht gain and body fat. This is however associated also with the will to become thinner and thinner even while loosing normal weight and beco

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ming underweight.

Patients suffering from anorexia deny their problems and refuse to see the danger they expose their body to. These perso

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ns are usually very preoccupied with calories, fat grams and weight and become often angry and irascible when help is offered. The constant

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

denial of having a major eating disorder turns into a difficult disease and also leads to a separation of the person from the society that

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

is willing to help.

Warning signs of Anorexia seem sometimes very hard to observe as patients do their best to hide and deny any symptom

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

or sign of their condition. They make huge efforts to avoid their family and friends to observe something is wrong as they are certain they

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

are very fat, must loose weight and no one can help.

Anorexia patients refuse to keep at least a minimal accepted weight for their own age

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

and height and become dramatically thinner every day; this is associated with a poor self image and low self respect. They seem to find ex

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

cuses every time for skipping meals, eat very few foods only with little calories, weigh frequently and are attentive to the smallest weigh

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

t change. The tendency of wearing large clothes is due to the need of hiding their body, excessive obsessive training program occupies a l

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ot of time in their lives. Time is also controlled by the need of looking carefully into the mirror, looking for flaws.

Anorexia sufferers

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

find excuses for skipping gatherings implying food and continuously complain about how fat they are. The most dramatic physical signs of t

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

he condition are low sexual appetite in men and irregular menstrual periods in women.

The two basic types of anorexia are:

1. Classic res

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

trictive Anorexia involves very little calorie intake and excessive rapid weight loss. The food income is mostly insufficient to maintain n

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ormal vital functions.

2. Purging Anorexia works through self induced vomiting and excessive use of laxatives. This is called bulimic anor

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

exia and associate low food intake with the need of purging after meals. Most patients with anorexia develop symptoms of additional bulimia

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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