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Advice Pool - Two Scientific Theories About Food Addiction - Are They Both Right
Several different theories about food addiction are being considered by the scientific community. Most of us have heard of the “thrifty gene” theory. This theory suggests that people who have this gene will eat more calo
According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
ries today as an instinctive response to the possibility of famine tomorrow.
Another theory suggests that overeating fats and simple sugars is a “rational addiction,” because the cost of withdrawal is higher than the co
Another theory suggests that overeating fats and simple sugars is a “rational addiction,” because the cost of withdrawal is higher than the co
; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.
Examples of combination products may in
Examples of combination products may in
t of maintaining the habit of overeating. The costs could include the physical symptoms of withdrawal from addictive foods, the costs of weight loss treatment, and the possible higher cost of buying more nutritious meals
lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.
The decisions made by government agencies and individual counselors depend on which of these theories they accept.
If the rational addiction theory is held to be true, laws might be passed to reduce the cost of highly
here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
nutritious vegetables and proteins, which are low in calories, and increase the cost of low-quality foods such as sugar and high-fat snacks, perhaps with new taxes. The financial costs of weight loss programs and medicat
d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.
Combination pro
Combination pro
ons could be lowered with subsidies. Health agencies might create educational and counseling programs to help obese clients make better, less irrational choices when they shop.
On the other hand, if there really is a “t
On the other hand, if there really is a “t
ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
rifty gene” that causes food addiction, scientists would look for ways to “turn off the gene” through new medications or gene therapy. Counseling would consist of helping people recognize their natural tendencies, and he
easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
p them create an environment in which more rational eating choices would be easier to make. Perhaps governments would regulate the creation and sale of high-fat, sugary foods as if they were an environmental hazard.
To
To
nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
etermine which of these theories can be used to explain the very high incidence of obesity and type-2 diabetes among the Pima Indians in the American Southwest, two professors from Arizona State University looked at the
and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
hopping activity at several Arizona supermarkets. The study compared the shopping choices at stores near the Pima community, which has an astounding diabetes rate of almost 50%, with those made by the general population
ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
t supermarkets in other locations.
The professors determined that the low prices of foods high in simple sugars has led to the over-consumption of these harmful foods in all populations, but that non-native people as a
The professors determined that the low prices of foods high in simple sugars has led to the over-consumption of these harmful foods in all populations, but that non-native people as a
ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.
Following aspects would a
Following aspects would a
group consume these cheaper foods in lower quantities than do the members of the Pima tribe as a whole. The study did not look at the shopping behavior of individuals.
This may mean that both the “thrifty gene” theory a
This may mean that both the “thrifty gene” theory a
dd to the challenges in developing combination products:
Which markets to tap where the combination products can do fairly well?
Which combination prod
Which markets to tap where the combination products can do fairly well?
Which combination prod
d the economic “rational addiction” theory are correct, and not mutually exclusive. It is true that foods made from white flour and sugar tend to be less expensive (per calorie) than higher quality foods containing prote
cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
n and whole grains. The easy availability of poor-quality foods, along with high-fat fast food, has had a striking consequence for all Western nations.
Some people do choose to avoid these fattening foods and eat health
Some people do choose to avoid these fattening foods and eat health
tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
veggies and low-fat meats instead, which lends weight to the thrifty gene theory. However, income does play a part. According to the U.S. Department of Health and Human services, “women of lower socioeconomic status are
t?
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
approximately 50% more likely to be obese than those of higher socioeconomic status.” This statistic includes all racial and ethnic groups.
The incidence of type-2 diabetes, hypertension and heart disease is going up fo
The incidence of type-2 diabetes, hypertension and heart disease is going up fo
ping new procedures for reviewing their safety, efficacy and quality.
Professional from academic institutions, pharmaceutical industries, health care indust
Professional from academic institutions, pharmaceutical industries, health care indust
all Western populations and the long-term effects of this illness are devastating both to the individual and society. In the general population, approximately one-third of American adults are overweight, and a third of
y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
hese are obese. The occurrence of obesity in the general population has almost doubled since 1960, and is quickly catching up to the high rates of obesity and diabetes among the well-studied Pimas.
Because it is estimat
Because it is estimat
.
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
d that obesity is related to a 10 to 50% increased risk of death from all causes, and the cost of chronic diseases associated with obesity are creating a drain on the national treasury, it is particularly important to fi
elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.
Companies that provide selfless information through particip
Companies that provide selfless information through particip
d a workable theory about food addiction. Perhaps if we gain a better understanding of why people overeat, in spite of obvious consequences, scientists will be able to find a cure for the international problem of obesity
tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products
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