Advice Pool - Health and Fitness

Eating disorders may very well start off as a preoccupation with food and body weight but there is definitely much more to these than just foods. Eating disorders usually are long-standing illnesses, which requi

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

re long-term treatment and are often accompanied by other psychiatric disorders, such as anxiety, depression and drug abuse.

Eating disorders can be fatal. They can inflict life-threatening medical complication

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

s including serious heart conditions (low blood pressure, slow heart rate, palpitations and heart failure) and kidney failure, which may ultimately lead to death. Learning about the disease and what causes it ma

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

y save us from these threatening complications.

What Factors Contribute to the Development of Eating Disorders?

Eating disorders have been found to be influenced by a variety of factors. Recent studies show th

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

e interconnection between the problem and certain biological, psychological and socio-cultural factors.

. Biological factors. Studies indicate that certain people may have a genetic predisposition to develop a

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

eating disorder and that it probably runs in the family. Several researches prove that having a biological mother or sister with an eating disorder (anorexia, bulimia, binge eating) increases an individual's li

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

kelihood of developing the same disease. A study involving twins also support this conclusion.

Scientific studies also found out that people afflicted with eating disorders have certain chemicals imbalances in

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

their brains. These chemicals are those which are responsible for controlling appetite, hunger and digestion.

. Psychological factors that may influence the onset or aggravation of eating disorders include low

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

self-esteem, feeling of inadequacy or helplessness in some aspects of life and depression, anxiety, anger or loneliness. They may have obsessive-compulsive personalities, which make it easy for them to stick to

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

their rigid diets and to deny hunger altogether. Persons afflicted with eating disorders may also be perfectionists and may never think that they would ever be thin enough.

Being overwhelmed by difficulties in

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

family or personal relationships, having a history of being teased based on body weight or shape or a traumatic past (example are being subjected to physical or sexual abuse) may increase the person's predisposit

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

ion to develop the disorder.

. Socio-cultural factors. Society may also play a part in the proliferation of the problem. It does not help that our culture promotes the "ideal figure" as that of the ultra-svel

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

te and waif-like figures sported by models and famous personalities. Neither does the media's unspoken promotion of the direct relationship between thinness and success or happiness help. All of these put undue

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

pressure, which may lead to the development and aggravation of eating disorders.

Several other events or situations may be associated with the development of eating disorders. Dieting and the positive feedback

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

given to people who lose weight may unconsciously precipitate the observance of excessive dieting. The consequent criticisms that are bestowed upon those who have gained weight may also be another cause. Peopl

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

want and need to be appreciated and some will go through extreme measures like excessive dieting just to achieve this.

Adolescents go through a series of bodily changes during puberty. Some children are early

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

bloomers and may find that their newly emerging bodies can be a source of unwanted attention. To cover up for these changes, some may enforce strict diets hoping that this will somehow stop or delay the changing

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

process. This may lead to the development of eating disorders.

In some other cases, a certain degree of thinness is a professional requirement. This is true especially in several sports, work and artistic are

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

nas. Take the case of models, actors and actresses who need to look good in order to succeed in their chosen field. Or those involved in sports such as figure skating, gymnastics, running and wrestling where mo

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

bility is enhanced by losing weight.

Eating disorders can take control of the lives of people afflicted with this condition. Knowing what causes the problem may eventually help us avoid it before it even begins

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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