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Advice Pool - Anorexia Takes Lives
Eating disorders are on a steady rise in a world influenced by Hollywood's and the fashion industry's standards of beauty. Sayings like: "You can never be too thin", peer pressure and daily m
According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
agazine covers with ultra-thin models or celebrities make us only too aware of our own flaws. What is not shown are the statistics: 20% of people with anorexia will end up dead.
Anorexia ner
Anorexia ner
; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.
Examples of combination products may in
Examples of combination products may in
osa, like most eating disorders, usually starts during puberty, but it can also affect adults and children. Recent studies indicate that the age of onset of anorexia is getting younger and yo
lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.
nger, starting as early as 7 years of age.
Though most commonly associated with teenage girls and adult women, it is estimated that 10% of reported cases of anorexia are boys and adult men.
Though most commonly associated with teenage girls and adult women, it is estimated that 10% of reported cases of anorexia are boys and adult men.
here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
hese numbers could be false, since anorexia is pegged as a "female disorder" and men might have difficulties admitting to the disease.
People who have anorexia are obsessed with being thin an
People who have anorexia are obsessed with being thin an
d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.
Combination pro
Combination pro
will usually go to any lengths to achieve and maintain this. They can't see themselves through others' eyes and often perceive themselves as fat. As a result, they will literally starve the
ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
mselves in the name of "beauty".
Obsession with calorie counting, taking laxatives and diet pills or diuretics (drugs that elevate the amount of urine excretion), sometimes bulimia (inducing
Obsession with calorie counting, taking laxatives and diet pills or diuretics (drugs that elevate the amount of urine excretion), sometimes bulimia (inducing
easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
omiting after a meal) and excessive exercising are the most common signs of this disease; as is hiding food or lying about food consumption. Food will be put in the mouth but then secretly sp
nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
t into a napkin. The affected person will chew very slowly to give the appearance of eating longer, i.e. he or she "finishes" at the same time as the rest of the table. Food will be pushed a
and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
ound in the plate, mixing it up so it's hard to tell how much he or she really ate. Though anorexics in general avoid high calorie food, they will sometimes eat a lot of junk food, especially
ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
candy, smoke and drink a lot of coffee (a natural diuretic) or tea.
Most people understand anorexia as the desire to be thin, but there is more to that. Very often anorexics feel that their
Most people understand anorexia as the desire to be thin, but there is more to that. Very often anorexics feel that their
ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.
Following aspects would a
Following aspects would a
life is out of control and that they have no power over things happening in their lives. The one thing they can control though is their body weight and how much they eat. Other emotions caus
dd to the challenges in developing combination products:
Which markets to tap where the combination products can do fairly well?
Which combination prod
Which markets to tap where the combination products can do fairly well?
Which combination prod
ng the onset of anorexia can be stress, anxiety, unhappiness and depression. The only way they know how to cope with these emotions and to express them is through having control over their fo
cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
d consumption.
What most anorexics seem to have in common is a background of abuse, be it physical, emotional and/or sexual, though not in all cases and sometimes, it is actually just about t
What most anorexics seem to have in common is a background of abuse, be it physical, emotional and/or sexual, though not in all cases and sometimes, it is actually just about t
tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
e physical appearance. Models, dancers or long-distance runners feel the need to be extremely thin to be on top of their game. Genetics also seem to be a factor: If one of the parents was an
t?
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
rexic, the children have greater chances of developing anorexia too.
If left untreated, anorexia can cause irreparable damage to the body and nervous system and in some cases, it can be fatal
If left untreated, anorexia can cause irreparable damage to the body and nervous system and in some cases, it can be fatal
ping new procedures for reviewing their safety, efficacy and quality.
Professional from academic institutions, pharmaceutical industries, health care indust
Professional from academic institutions, pharmaceutical industries, health care indust
. The most common cause of fatalities due to anorexia is heart disease. Anorexia causes irregular heart rhythms, which can eventually result in smaller heart muscles.
Due to hormonal change
Due to hormonal change
y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
, anorexia can cause retarded growth, bone loss, infertility and in women, the absence of menstruation. The lack of minerals and electrolytes in the body causes an imbalance and fatigue can s
.
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
t in. The imbalance itself can also become life threatening. Another uncomfortable side effect of anorexia is bloating and constipation. Untreated anorexia can cause seizures, leaving behin
elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.
Companies that provide selfless information through particip
Companies that provide selfless information through particip
irreparable nerve damage.
Treatments for anorexia can include counselling with a nutritionist, psychotherapy, family counselling and in some cases, medications; antidepressants specifically.
Treatments for anorexia can include counselling with a nutritionist, psychotherapy, family counselling and in some cases, medications; antidepressants specifically.
tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products
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