Advice Pool - Health and Fitness

The desire of having a beautiful, slim body determines girls and young women to take drastic actions. The society we live in puts a lot of pressure on the shoulders of young girls

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

by establishing and supporting exaggerated physical features as ideals of beauty. Teenage girls struggle to get noticed and sustain assiduous efforts in their attempt of improvin

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

g their physical appearance. Their constant preoccupation with body weight sometimes becomes an obsession and many young girls develop eating disorders.

Eating disorders are cons

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

idered to be serious illnesses and they may even lead to death. These disorders are basically mental conditions that are characterized by unhealthy behavior, scarce eating and obs

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ession with being overweight. Anorexia (Anorexia Nervosa) and bulimia (Bulimia Nervosa) are the most common and the most dangerous eating disorders.

Anorexia affects persons of a

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ll ages and regardless of sex. However, young girls are more susceptible to developing anorexia, due to their ambitions and desires of being thin. Girls with anorexia eat very lit

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

tle food and sometimes they even constrain themselves from eating any food at all. Abstinence from food leads to serious complications and girls with anorexia often develop other

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

diseases due to their bad eating habits. The lack of vital nutrients triggers a lot of changes inside the bodies of anorexics, making them feel weak, tired, anxious, confused and

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

psychically unstable.

Girls with anorexia also experience a lot of physical changes. Their growth is dramatically slowed down; they suffer from stomach aches and internal disturb

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

ances, migraines, heart problems, bad circulation of the blood, hair loss and dehydration. Inappropriate eating habits cause hormonal unbalances and girls with anorexia often suff

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

er from amenorrhea. This condition refers to irregular menstruation and girls with anorexia even experience stops of their menstrual period due to small levels of estrogen. Amenor

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

rhea often leads to weakness of the bones, corrosion of the teeth and fragility of fingernails.

Girls with anorexia have obsessive thoughts about food and being fat. They careful

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ly count the calories they consume and often exhaust themselves by doing long, tiring physical exercises. Despite the efforts they sustain in order to keep fit and lose weight, gi

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

rls with anorexia are never content with their body weight and physical appearance. They have a distorted perception of their body image and always consider themselves to be fat,

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

even if their body weight is considerably lower than it should be.

Young women and girls that have careers where a slim body is a necessity (gymnastics, modeling, ballet) are als

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

o susceptible to developing an eating disorder.

It is very important to act quickly when dealing with eating disorders. Girls with anorexia are often unaware of the dangers they

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

expose themselves to and most of them deny having a problem. Some of them, however, are willing to sacrifice their health and jeopardize their lives only to be admired for their s

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ilhouette. Because girls with anorexia are usually unable to overcome their illness on their own, they should be provided with plenty of support and encouragement from their famil

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ies and friends.

Anorexics feel lonely and unhappy and have low self-esteem and self-respect. By proving to people who suffer from anorexia that low body weight isn’t the most im

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

portant thing in the world and by showing them that they are unique and beautiful regardless of their physical appearance, you can help them make the first steps towards recovery.

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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