Advice Pool - Health and Fitness

Travelling, whether it is for work, vacation, or a simple family trip, is a common

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

excuse for not exercising. When you add fast food (on a road trip), dining out (w

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

hich normally means larger portions), and junk food (hey, you're on vacation - why

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

not splurge?), you can put on a few extra pounds very quickly. But you can find a

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

way to exercise when you are on the road. Here are three simple exercises you can

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

o without weights:

1. Push Ups: This is a slight modification on a classic exerci

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

se. Make a traditional push up more difficult by raising your feet. Prop your feet

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

up on a small bench, a chair, or even on a bed. The elevation increases the intens

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ity. Do as many repetitions as you can.

2. Single Leg Squats: I am sure you are f

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

miliar with regular squats (you know, where you have two feet on the floor). When

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

you are traveling and don't have any weights to work with, you can try single leg

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

squats. Make sure you can keep your balance though. A good idea is to stand near a

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

wall or a door frame so that you can balance yourself. As with the push ups, see h

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ow many repetitions you can do.

3. Crunches: Simple crunches can be done nearly a

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ywhere. Lie flat on your back with your feet flat on the floor. Crunch up and touc

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

h your elbows (with your arms bent behind your head) to your knees. Keep your back

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

flat on the floor at all times (this ensures that your back stays supported). Once

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

again, repeat until failure.

There you have it: three simple exercises that you

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

an do virtually anywhere. The intensity and number of repetitions are completely u

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

p to you. But with these three simple exercises you work all of your major muscles

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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