Advice Pool - Health and Fitness

This article is not just for athletes. It is also a good article for those considering themselves fitness enthusiasts and folks wanting to learn more about how to maximize their body's abilities.

First, I want to address a growing trend in training. Hopefully, it will come to an end. Two systems doom to fail are HIT and Chaos Training. Without a plan, your success will be a long shot or nothin

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

g more than re-inventing a wheel, period. To be a “jack of all trades”, but a master of none is a ridiculous way of trying to train, especially on an advanced level. Too many athletes have injuries from not progressing correctly and attempting power movements when basic movements remain uncorrected. Too many people wishing to be “hardcore” try boot camp style workouts or a “cookie cut” workout

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

rom a website or magazine, only to find they do not understand the movements and end up overloading the wrong muscles (usually the back muscles) at the wrong time. It is a real pity. I would call it laziness of mind and body development. Understanding fundamentals of training needs to be addressed by everyone choosing to get serious with training. This idea especially holds true for athletes, t

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

hat they will need a solid foundation free of motor skill dysfunction and injuries, to compete at maximal levels.

I am not going to take time to dilute verbiage for this article. I highly suggest if you don’t know what I am talking about look it up.

A strong foundation is of the utmost importance for both athlete and fitness enthusiasts. Every athlete should go through a period of low specifi

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

anatomical adaptation (AA) before increasing the specificity of the training regiment. I will outline the starting point of AA in this article. Before embarking on any regiment, it is very important to know your strengths and weak points. It may be wise to get a few consultation sessions specifically for physical assessment by a knowledgeable trainer.

First, posture needs to be addressed. The

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

spinal cord must be protected from “non- contact” injuries while training. In general, the spine will be kept in its strong position or “neutral” position throughout the workouts and daily task (if at all possible). This article will not go into too much detail of postural corrections. Throughout training you will need to be “body aware” and able to adapt proper position of the spine to create

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

an optimal environment of lifting. The strong postural positioning of the spine is on a very individual basis. When working out and going through daily life one should be able to “find the neutral spine” (McGill 2006). For most healthy individuals this is an equilibrium position between spinal flexion and extension. For some who carry back injuries, more flexion may be needed to hold a modified

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

neutral spine.

This can be a very frustrating period of time, but it is a very important step to possessing strong posture. Once the neutral position is found, you must practice holding or bracing it at all times (if possible). The abdominals should feel tensed when in proper neutral positioning. This signifies the lumbar spine is not being loaded unnecessarily and the entire core complex is b

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

eing properly “readied” to bear weight. For any athlete, being able to hold strong posture in 3D will be a very strong asset to performance abilities. When I say 3D, I mean being able to be strong in all planes of motion (sagital- squat, pushup, arm curl (frontal- lateral lunges, jumping jacks, laterals arm raises) and (transverse chops, torso twist, scorpion). For instance, a football tight en

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

will have to hold his position and most likely break away from a defensive player. He may also have to run a certain route and catch a passed football. If he falls short of having strong posture and being able to hold balance and maximal speed in 3D, his game performance will be drastically hindered.

Next, abdominal bracing and muscle awareness goes hand in hand with posture and being aware o

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

spinal position. We are very visual creatures and learn most things from sight and touch. Being able to move your body, “consciously” on command, falls into the first part of AA. I am a big advocate of the fact analysis causes paralysis. However, before something becomes subconscious and of secondary nature like breathing, it must first be conscious, especially when we speak of motor skills. S

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

o flexing each muscle in turn is a great way to learn how the muscles flex and what muscles assist in the tension. At the same time being very aware of abdominals being braced or loss of abdominal bracing will be a major asset. Pavel has a good look at strong posture for working out. Drop your shoulders to a low position. Stand straight up with arms at your sides. Without bending over, reach do

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

n as low as possible with your fingertips. Tense your armpits to push your shoulders down and back (Pavel 2004).The abdominals will be braced prematurely simply from being in the proper standing position. It is also, wise to palpate different areas of exertion. Whichever muscle you flex, you feel to make sure it’s flexed and help your mind and body understand what a tense muscle is. To feel for

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

abdominal bracing, palpate the connecting point of the rectus abdominus and internal obliques.

Breathing will go hand and hand with abdominal bracing. To have a strong posture and braced abdominals, you must be able to maintain it. Breathing should be maintained in the abdomen, this will keep from draining the secondary respiratory muscles and losing the strong posture. Pavel has a great dril

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

to engage the intra abdominal breathing. Basically, lie down and place an object like your shoe on your chest and another on your stomach. Breathe in through your nose and bring the air into your abs making the object on your stomach rise without moving the object on your chest. Exhale through the mouth and release the air in your belly contracting the abdominals at the same time. Try to sense

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

the feeling in your abs (Pavel 2004). Do not confuse this with hollowing the abs.

Next, we will need to correct harmful movements before the strong posture was assumed. Here you practice “hip hinging”, which is keeping your spine in the neutral position and allow your hips to control flexion and extension (McGill 2006). Body weight type movements will do just fine here. The key is to keep the

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

abdomen braced and really hone your skills with proper intra abdominal breathing and abdominal bracing. Remember, you will need strength in 3D, so make sure to address those areas. You are still analyzing movements, so palpate your back, hips and abs to feel for proper movement and tension. In this phase the focus is a level of endurance with the muscles remaining tense for a given time period.

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

Many forms of isometric hold exercises would work well here. The exercises using repetitions should be done at a slower tempo. When complete, the nervous system should be able to recruit more motor units for use efficiently than before. Train smarter not harder.

The next step is to begin progressing your abilities in different forms. This is also when the broader sport specifics are put into p

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

lace. The strong posture should become subconscious and corrected. The variables for AA will depend greatly on the weak points, specific sport needs, and frequency of training.

The following is a progressive variable checklist from Gary Gray:
1. Bilateral stance
2. Unilateral stance
3. Arms and leg counterbalance
4. No arms
5. Eyes closed
6. Varied surfaces

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

. Reduced base of support
8. Dynamic movement
9. Increase R.O.M. (range of motion)
10. Increase Speed
11. Reaction
12. External Kinesthetic Stimulus

Reference:
1. Tsatsouline, Pavel, (2004) The Naked Warrior, Dragon Door Publication, St. Paul MN.
2. McGill, Stuart PhD, (2006) Ultimate Back Fitness and Performance 3rd Ed., Wabuno Publishers, Ontario Canada

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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