Advice Pool - Health and Fitness

While I was at university, my house-mate would nip off two three evenings a week to the local sports centre to aerobics. Each time she would say ‘why not come? You’ll love it.’ I would not dignify her with a reply other than a derisory snort; I was not that sort of perso

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

n. The prospect filled me with horror; a room of health-mad skinny women in extremely tight clothing torturing themselves to excruciating music. I could not even contemplate it without feeling queasy. I noticed however that my house-mate started to look fantastic, in fa

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ct everyone noticed; she lost weight and looked toned; she had a spring in her step, she glowed. I rather wanted to lose weight, and glowing was fairly high on my list of priorities, but I still couldn’t bring myself to go; I didn’t have the right clothes to wear, and cou

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ldn’t face battling lycra outfits in a brightly-lit changing room. I knew that I would feel chubby, lumpy, and uncoordinated, so I dug my heels in and sat at home watching Eastenders and eating biscuits.

Several years later I found myself with a delightful young child, a

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

nd over a stone of un-delightful extra weight. The prospect of a swimming costume filled me with terror, but I was desperate enough to start swimming two or three times a week. The exercise was challenging but relaxing, and gave me some freedom from being a working mothe

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

r. I started to (shock horror) enjoy it; my swimming costume became baggy; then I really started to enjoy it. One day the swimming lanes were closed and my only option was; OH NO an aqua-aerobics class. I was consumed with dismay; did they not understand that I couldn’t

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

possibly participate in such a loathsome pursuit; I was not that sort of person. The other option was to go home unexercised, and so I reluctantly stepped into the unknown world of aqua aerobics; it was great. It was true that I would not choose to listen to the music a

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

t home, but it seemed perfectly normal and even enjoyable as part of the class. There were no skinny health-mad women making me feel lumpy and uncoordinated, just lots of nice people enjoying themselves. I left feeling pink and puffed-out but elated, and booked myself in

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

to the next session. After a few weeks, I needed more, and emerged onto dry land for a Bums and Tums class. I loved it; I am not sure how much exercise I got because I couldn’t understand what was happening even though it seemed to make sense to everyone else. I perseve

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

red until I could decipher the new language of aerobics. Three months later I was hooked; I was Vikki Scovell, you know the one who is always at class. I lost weight, my arms and legs grew toned, and my tummy was flatter than it had been in years. I was happy, I glowed,

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

and everyone noticed the change. I went shopping and bought a new wardrobe of fitted clothes. I screamed with wild delight in the changing rooms the first time I slipped into a size 12 dress, and ceremonially packed a bag of size16 stuff for the charity shop.

That was

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

seven years ago, and I have never looked back. I continued to exercise through my second pregnancy, and am proud to have gone into labour during an aqua aerobics class; the only time I have ever left a class early (only 10 minutes). Now that I am teaching aerobics and Yo

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ga every day I feel privileged to watch other people take control and transform their lives through attending classes. I have watched people battle weight-problems, lack of confidence, and deal with personal tragedies. Friendships are forged, interests are created, and I

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

have seen the most graceless of people gain the poise and control of a ballerina. Group exercise changes people’s lives; I know that for a fact. There is a vast variety of group exercise for every social group, fitness level, and age; there is truly something for every

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

one. Some of the many benefits to attending group exercise include:

• Having a qualified instructor to guide you, and teach efficient and safe techniques.
• Feeling a sense of camaraderie, and meeting new people.
• Building personal confidence, body awa

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

reness and coordination.
• Benefiting from a wide range of different disciplines, and a huge variety of class times to fit your schedule.
• Learning something new, challenging yourself, and feeling a massive sense of achievement when you do something for the fir

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

st time.
• Releasing stress, and relinquishing your responsibilities; let your teacher take control for an hour. When you are following a routine and participating in class you cannot focus on your every-day troubles and cares.
• Improving physical and mental we

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

llbeing, becoming fitter and feeling happier; recent studies at the University of Strathclyde took women with early stage breast cancer and sent them to 2 group exercise classes a week, and one session on their own. After 12 weeks the women showed significant increases in

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

their psychological and physical wellbeing including reduced depression and a feeling that their overall quality of life had increased, as well as increases inhealth and fitness. There as many reasons to attend a class, as there are classes to try; look out in your loc

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

al community centers, school halls, fitness clubs, and parks. Go and try something this week; attending class changed my life for the better, and it may just do the same for you in one of a million different wonderful ways.

Until next time,
See you in class!

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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Advice Pool - Group Exercise Classes Changed My Life- Get Fitter, Lose Weight, and Feel Happier!

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