Advice Pool - Health and Fitness

Stamina is the endurance you build to resist fatigue. It’s importance toward your d

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

aily life is greater than you think. Developing your stamina not only gives you the

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ability to continue training under stressful situations - which makes you a lot str

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

nger (i.e. weight lifting, body weight exercises), but increasing your stamina also

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

increases your resistance to common health problems such as heart disease.

There

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

are many more ways to develop your stamina other than running

Most people abso

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

utely HATE running. The feeling of being out of breath often scares them, so they s

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

imply don’t run - they continue to be out-of-shape because of a little FEAR. Well l

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

isten up: FEAR is a mental thing - it’s not even real, it’s all in your head. Many

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

eople define fear as being scared, adrenaline dump, etc... Those aren’t the real def

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

initions. The REAL definition of fear is: False Evidence Appearing Real.

F.E.A.

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

R. = False Evidence Appearing Real

Don’t let the fear of running or being breat

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

less ruin your personal fitness. Because there are plenty of other ways you can boo

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

st your stamina without ever leaving the safety of your home.

1. Jump Roping

2. Hi

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ndu Squats

3. Hindu Pushups

4. Running in Place

5. And many more

If you’re the t

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

pe of person who hates running or just doesn’t feel like going outside in the hot/co

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ld weather, don’t worry about it. You can get in shape right in the comfort of your

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

own home and still be able get the fitness results that you want.

Try the above ex

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

rcises that I listed and you’ll get even better results than running can ever give y

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ou. Try them all and your stamina will have a significant increase within two weeks

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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