Advice Pool - Health and Fitness

A regular exercise program is a key component to keep fit at all times. It is ben

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

eficial when we grow older. If you are obese you stand a greater chance of develo

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ping diseases like heart problems, hypertension, strokes, breathing problems or s

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

leep apnea. Hence, eating the right type of food is also important along with exe

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

cises.

It is important for you to exactly know how fat you are. You may have exc

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

essive fat on the hips or buttocks, which is known as “pear fat”, or if you devel

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

op excessive weight around the waist it is termed as “apple fat”. Being apple fat

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

is a greater worry to your health because you are at high risk for diseases like

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

diabetes, cancer or heart problems. If your waist area measures more than 35 inch

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

es, then you are ‘apple fat’. If you measure both the sides of hip and waist then

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

divide both the measurements and if it exceeds more than 0.8 you need to work ha

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

rder to burn the extra weight.

Physical training helps improve the bone structur

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

. It prevents many problems such as bone cracks, osteoporosis etc. It also makes

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

your bones stronger along with strengthening the muscles. To make your body fit

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

within a shorter period; it is better to practice both aerobic and anaerobic exe

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

rcises. Aerobic exercises shed your excessive weight where as the anaerobic ones

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

uild your muscular strength. In order to perform your anaerobic exercises, it wou

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ld be better to start with a few slow aerobic exercises. If you are start an exer

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

cise program begin with aerobic exercises for a few days and then gradually start

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

anaerobic exercises. Before beginning any fitness program consult your physician

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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