Advice Pool - Health and Fitness

For many people in today’s busy world it’s quite easy to come up with an excuse for not being in shape and exercising regularly. Some of the more common one

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

s are “I’m too busy”, “There aren’t enough hours in a day”, and “I’m so tired after work and taking care of the kids all day”. However most of these are jus

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

t that, excuses. Unless your doctor has informed you that you should not exercise, some form of activity or physical fitness should be a priority on everyon

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

e’s daily routine. The key is realizing that your health is an important part of your life, and should be made a priority.

The best way to keep is shape is

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

to be involved in some sort of physical activity on a regular basis (at least 3 times a week). If you can find a sports activity like swimming, tennis, racq

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

uetball, basketball, baseball, softball, running, or karate that you enjoy this is just as effective as a regular exercise routine. If it’s something you en

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

joy chances are you won’t think of it as drudgery and will look forward to doing it.

For those of us who don’t participate in some form of sports on a regu

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

lar basis we are going to have to come up with regular exercise program. One of the most successful methods is to get up half an hour earlier in the morning

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

and exercise. If you really like your sleep this may be hard, but if you exercise at night it’s much easier to say “I’m too tired today” and skip it. If you

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

have kids around the house you are also setting a great example about how important taking care of your health and your body really is.

The first option t

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

o consider is choosing a gym. While a gym can be expensive you will have access to a wide variety of equipment and machines that you could never afford or f

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

it into your house. You will also have access to health professionals like personal trainers.

If a health club is too expensive or doesn’t fit your lifesty

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

e consider a home gym. You can usually purchase a set of free weights, exercise bench and floor mat for under $200. If you like exercise machines such as st

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

air climbers or stationary bikes keep in mind some of these can be expensive. Watch for garage sales where you can pick up second hand units at a discount.

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

Some people prefer the guidance that an exercise tape can give you. While these are good choices if you are like most people, you’ll get tired doing the sa

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

me routine after a few weeks. Consider choosing a series of tapes, borrowing some from the library, or trading them with a friend. With the expansion of fit

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ess programs on cable TV you also have access to a wide variety of programs. If the instructor you like isn’t on when you exercise consider using your VCR o

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

r Tivo to time shift your viewing. Once you start exercising regularly make sure you vary your routine and change it from time to time. This not only keeps

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

you from getting bored but it keeps your body from getting used to the exercises. Most fitness experts recommend changing your routine every 6-8 weeks. As

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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