Advice Pool - Health and Fitness

Did you know that walking is the number one participation sport in the world? Walking is one of the best things you can do for overall health and wellness. When you walk

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

you use more muscles than any other sport. In fact, walking uses almost all of the 650 muscles and 203 bones found in the human body. So what are you waiting for?

There

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

is not much involved in starting a walking program. You can start immediately and you don’t need a coach to teach you how to walk. The equipment required to start is mi

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

nimal and relatively inexpensive.

Important Equipment

The most important piece of equipment you will need is a good pair of walking or running shoe. Most shoe stores a

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

d sporting goods stores should be able to supply you with a good selection. You can also check out some of the online stores, you will find some good sources at DrLeonar

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ds.com or FootSmart.com. You may also want to think about getting yourself a pedometer. Pedometers are handy little gadgets that can measure your distance and time and h

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

elp you keep track of your progress.

Why am I walking?

Now that you have your equipment and are ready to go, it might be nice to know why you are starting a walking prog

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ram. The health benefits of walking are many and include the following:

· Helps with weight loss.

· Helps to reduce blood pressure

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

· Reduces the risk of type 2 diabetes

· Relieves stress

· Boosts overall energy levels

· St

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

rengthens the heart and reduces the risk of heart disease

· Studies have shown that walking relieves depression and anxiety

· S

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

trengthens your body

· Burns almost the same amount of calories as running

How should I start?

Since walking uses almost all 650 of your muscles it i

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

s a very good idea to warm up before you begin a walk. This will loosen up your body and help to avoid injury.

How long should I walk?

You should build up to walking fo

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

about one hour. Your current fitness level will determine the length and time of your first walk. Some people will only be able to walk around the block, others will a

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ble to walk the full hour. Do what you feel comfortable with and build from that point. Keep a log to measure your progress. As you become fitter, increase the pace and

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

distance.

Personally, I like to measure my walks in distance. A pedometer will be of great assistance. Measuring your walk in distance helps to compensate for days whe

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

n you might walk a little slower or faster. After your first few walks try to achieve a brisk pace where you may be puffing a little but you can still talk. Remember, th

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

re is not much difference in the amount of energy (calories) expended by walking or running a specified distance.

After you have finished your walk don’t forget to cool d

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

own. Try to spend about 5 minutes walking slowly. This will allow your heart, lungs and blood flow to return to normal gradually. This decreases strain on your heart and

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

can help to prevent muscle strain and soreness.

JUST DO IT!!!

Hey, you’ve seen the commercials. Now you just have to commit yourself to walking on a regular schedule.

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

Make it part of your routine just like brushing your teeth. It’s easy to do and doesn’t require special training or equipment. Just do it!

Copyright 2005 Michael Brook

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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