Advice Pool - Health and Fitness

Here are some helpful pointers to keep in mind when choosing your next frame. The frame needs to be in proportion to your face. That

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

is the smaller frames are best for smaller faces. Another trick can be contrasting the frame shape with the shape of the face.

Bal

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

nce out the features. Small or delicate faces with thin hair, lips and eyebrows should choose a smaller, delicate frames and vis ver

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

a. Short faces can be made to look longer in a high-placed, light coloured temples. Long noses or wide set eyes look best with a hea

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

y, dark bridge that sits low on the nose. Small noses or close set eyes look best with a high, thin, light bridge. Rimless styles ar

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

also flattering. Close set eyes look best with frames that have a clear or lightly coloured nose area. Fuller faces should be paire

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

d with wide styles that don’t sit on the cheeks.

Round
The frames should make the face appear longer and thinner. In general,

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ook for frames equal to or slightly wider than the broadest part of you face. Minimise the curves and add definition with soft, angu

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ar rectangular styles. Higher temples will create a longer profile. Glasses with brow bars also pull the attention upward, making th

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

face appear longer. Therefore suggestions include wider frames with angular rectangular styles.

Oval
Almost any style works f

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

r an oval face. Square shaped frames with gently rounded edges and higher temples also look good on an oval face.

Square
To re

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

duce the angles of the square shaped face with its strong jawline, broad forehead and wide cheekbone, use soft, curvy styles that wi

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

l give the face some definition. Higher temples or cats eyes will lengthen the face. Classic ovals are a perfect choice.

Rectangula

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

Widen and shorten the face with styles that don’t extend beyond the widest part of the face. Wear round or square shapes. The

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ld John Lennon styles look great on this face. Frames with short horizontal and long vertical lines also work. Decorative or contras

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ing temples add width to the face.

Triangle
This face has a wide jaw and narrow forehead. Soften the lower portion of the face

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

by accentuating the eye area. Temples should be placed high. Frames can be top heavy and angled inwards at the bottom. Styles like

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ats eyes should be angled at the top corners and wide enough to balance the jawline. You can also try semi-rimless frames (metal fra

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

es with rimless bottoms).

Heart
Minimise the upper portion of the face by choosing frames no wider than the forehead and angli

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

g outwards from the bottom corners. Temples should not be placed too high. Suggestions include very light colours and rimless styles

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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There are steps you can take to help change or break these patterns. You've already identified the pattern. The next step is to identify separately and together what you want to do differently.

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