Advice Pool - Health and Fitness

Reading, and other ‘close vision’ work, is probably one of the greatest causes of poor eyesight – but it doesn’t have to be. Here, I’m going to tell you how to make reading a pleasurable experience which is totally safe for your eyes, and won’t result in progressively worse eyesight. Don’t read when tired or sick. The rule of thumb here is to read or perform close work only when your

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

energy is high: when you are ill or tired, get plenty of rest and sleep. Yes, I know, if you have to read for your job, you may not have the option, but at least you can avoid making it worse by not using your eyes too much after work.

Don’t read for extended periods in poor light. Nature, or outside solar light, gives us about 10,000 watts of light. Inside lighting is very dim in

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

comparison, about 150-200 watts at best. Most people read with 60-100 watt bulbs or less, and strain their eyes. If you have trouble reading in dim light, your eyes will strain and weaken even more.

It’s best to read in daylight, with the sun or outdoor light coming through the window onto your reading or working material. Or better yet, do your reading or close work outdoors! At ni

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ght, shine a bright bulb - 150-200 watts - onto your reading material to make it clear, and lessen eye strain. Adjust the light so it does not cause glare on the page. Even better, use a FULL SPECTRUM LIGHT BULB. If you don’t know where to get these from, do a google search for ‘full spectrum lighting’ to find a supplier near you, or one that will ship to you. Keep a Good Posture Whi

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

lst Reading. Poor posture while reading is a major cause of weakened and fatigued eyesight. Avoid slumping or hanging or craning your head down while reading. Sit comfortably erect.

A slumped head position causes gravity to pull down on the eyeballs, placing strain on the eye muscles, which have to hold the eyes back in the sockets.

Holding this 'neck-bent downward’ position cause

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

lengthening/flattening of your eyeball, resulting in myopia or nearsightedness.

Hold your book or reading material parallel, about twenty inches from your eyes. Holding the print too close to your eyes is also a major cause of myopia.

Don’t Read for more than 30 minutes at one time. 30 minutes is about the maximum time most people’s untrained eyes can handle without strain or fati

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

gue.

Read for a bit, then get up and walk around, stretch or go outside for a breath of fresh air.

Look into the distance. Take a deep breath, bend over and rub your face, forehead and around the eyes, exhale and stand up straight. Inhale again and bend backward, then to each side, and exhale and relax your gaze. Close your eyes and place your palms over your eye sockets and do som

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

e palming (see the next chapter)

Avoid Straining. Strain is the major cause of bad eyesight. Straining to "see" any object, far or near, which you are unable to see clearly, places a heavy strain on the eye muscles. It’s just like trying to lift a heavy weight that your body is not conditioned to cope with, it will strain and damage your tendons and muscles.

Other ways to strain y

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

our eyes include - long exposure to cold wind directly into the eyes, bright artificial lights, (especially fluorescent lights), watching too much television and staring too long at a computer screen (my favorite!) Look up regularly and gaze into the distance. This is probably the most important eye habit you can practice while reading, doing any close work or watching television.

T

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

his exercise keeps the eye muscles flexible and stops them from getting into a frozen position.

Simply look UP from your close-work every five minutes and gaze (focus) at a distant object for five seconds. This exercise prevents eye-muscle cramping and also relaxes the eye muscles. During close work, the Eye Muscles contract to properly focus the lens. These muscles kept in constant

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

contraction for long periods, tend to get cramped, just like your arm muscles would do if you held a barbell in a fully flexed arm curl position for several minutes. This was the hardest one for me, as I do a lot of computer work, and often, I get so involved with what I’m doing, I totally forget to look away. Sometimes, hours will pass before I realize I haven’t looked up from the s

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

creen even once! To force myself to do this, I found a simple, free software program which I installed on my computer – it’s called Break Reminder, and every 6 minutes, is locks me out of the computer and turns the screen black for a few seconds.

At first, it really irritated me, as it always seemed to happen when I was in the middle of something really intense, but after a while, I

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

got used to it and now I never forget to look up every 6 minutes to relax my eyes! Avoid Close Work During and After Meals. Dr. Sasaki, a Japanese Eyesight Specialist states that you can add twenty years to your life if you don’t read while eating, and go outdoors after meals for at least 30 to 60 minutes. I don’t know if he’s right about that, but it’s kind of obvious that if your

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

stomach is pulling all your bodies energy and blood supply to digest a meal, your eyes are better to be rested at this time, and not working flat out! You wouldn’t go to the gym, minutes after eating a meal, so it makes sense not to ‘send your eyes to the gym’ either, by forcing them to work hard, during or just after eating!

Avoid ‘Squinting’. Learn to see without muscular effort.

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

The eyes naturally 'squint' in bright light, snow or water reflection. Other than that, squinting to read or see an object only weakens your byesight. Avoid squinting by consciously relaxing the eye brows. Special Reading Technique to Improve Vision. This one’s a bonus… I found this awesome technique recently. It takes a while to get used to it, but it really helps your eyes and make

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

reading much easier… … "When reading, you should look at the white spaces between the lines and not directly at the lines themselves. The reason for this is that there is no effort involved in sweeping your eyes over a plain white background. Fixing the eyes on individual words and letters involves strain, and strain hurts your vision. When a person with normal sight regards the whi

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

te spaces with a sweeping shift across the page from margin to margin, he can read easily, rapidly and without fatigue. If the same person looks at the letters, the eyes grow tired and the vision becomes poor. People who cannot read well at the near point always tend to fix their attention on the print. Consequently they see worse. Improvement cannot take place until they learn to lo

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ok at the white spaces between the lines.

Reading can be improved by improving the power to remember or imagine whiteness. This improvement can be achieved in the following way… Close your eyes and imagine something even whiter than the page before you - white snow, white linen, a white board. Then open your eyes again. If your mental images of whiteness have been clear and intense,

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

you will find that the white spaces between the lines will appear for a few moments to be whiter than they really are. Repeat this process as a regular drill. When your imagination of whiteness has become so good that you n constantly see the spaces between lines as whiter than they really are, the print will seem blacker by contrast and the eye will find itself reading easily and w

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ithout effort or fatigue” I love this technique. Not only does it help your eyes and make reading more relaxed, you will find that you actually read many times faster than normal!

Learn about more techniques and resources on how you can improve your eyesight naturally and safely at

eyesight-tips-101.blogspot.com

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

Depression is a condition characterized by unhappy, hopeless feelings. It can be a response to stressful events, hormonal imbalances, biochemical abnormalities, or other causes. Mild depression that passes quickly may not require any diagnosis or treatment. However, when depression becomes recurrent, constant, or severe, it should be diagnosed by a licensed counselor, psychologist, social worker, or doctor.

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